NTR 368

Cat. No. 2087

NTR 368 Ac-Ala-Thr-Leu-Asp-Ala-Leu-Leu-Ala-Ala-Leu-Arg-Arg-Ile-Gln-NH2

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Alternative Name: Neurotrophin receptor (368-381) amide

Biological Activity

Peptide fragment corresponding to residues 368-381 of the human p75 neurotrophin receptor (p75NTR). Forms a helical structure in the presence of micellar lipid. Induces apoptosis in human neuroblastoma cells in vitro.

Technical Data

M.Wt:
1565.87
Formula:
C69H124N22O19
Sequence:
ATLDALLAALRRIQ-amide

(Modifications: Ala-1 = N-terminal Ac, Gln-14 = C-terminal amide)

Solubility:
Soluble to 1 mg/ml in water
Storage:
Desiccate at -20°C
CAS No:
197230-90-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Hileman et al (1997) A cytoplasmic peptide of the neurotrophin receptor p75NTR: induction of apoptosis and NMR determined helical conformation. FEBS Lett. 415 145. PMID: 9350985.

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Citations are publications that use Tocris products.

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Keywords: NTR 368, supplier, p75NTR, fragment, induces, apoptosis, Neurotrophin, Receptors, p75, Trk, RTKs, Receptor, Tyrosine, Kinases, NTR368, Tocris Bioscience, Trk Receptor products

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