Cat. No. 1048
Chemical Name: 1-(1,3-Benzodioxol-5-ylcarbonyl)pip
Biological ActivityA centrally active selective potentiator of AMPA-mediated responses. Facilitates memory retention in rats.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Yamada et al (1998) AMPA receptor activation potentiated by the AMPA modulator 1-BCP is toxic to cultured rat hippocampal neurons. Neurosci.Lett. 249 119. PMID: 9682831.
Vanove (1997) Effects of AMPA receptor positive modulators on amphetamine- and dizocilpine-induced locomotion. Eur.J.Pharmacol. 332 115. PMID: 9286612.
Desai et al (1995) 1-BCP, a memory-enhancing agent, selectively potentiates AMPA-induced [3H]norepinephrine release in rat hippocampal slices. Neuropharmacology 34 141. PMID: 7542369.
Arai et al (1994) A centrally active drug that modulates AMPA receptor gated currents. Brain Res. 638 343. PMID: 7911064.
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Keywords: 1-BCP, supplier, Modulates, AMPA-mediated, responses, Glutamate, Receptors, iGlur, Ionotropic, Tocris Bioscience, AMPA Receptor products