Cat. No. 1453
Chemical Name: (2R)-2-[2-[(1R)-1-(4-Chlorophenylet
Biological ActivityH1-receptor antagonist. Clinically-used antihistamine.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Nair and Schwartz (1983) Effect of histamine and histamine antagonists on natural and antibody-dependent cellular cytotoxicity of human lymphocytes in vitro. Cell.Immunol. 81 45. PMID: 6225527.
Dorsch et al (1982) Histamine1-histamine2 antagonism: effect of combined clemastine and cimetidine pretreatment on allergen and histamine-induced reactions of the guinea pig lung in vivo and in vitro. Agents Actions 12 113. PMID: 6177209.
Hartmann et al (1981) Modulation of histamine-induced bronchoconstriction with inhaled, oral, and intravenous clemastine in normal and asthmatic subjects. Thorax 36 737. PMID: 7330790.
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Citations are publications that use Tocris products. Selected citations for Clemastine fumarate include:
Nörenberg et al (2011) Clemastine potentiates the human P2X7 receptor by sensitizing it to lower ATP concentrations. J Biol Chem 286 11067. PMID: 21262970.
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Keywords: Clemastine fumarate, supplier, H1, antagonist, Receptors, Histamine, antihistamine, histaminergic, Tocris Bioscience, Histamine H1 Receptor Antagonist products
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High affinity H1 antagonist; anti-inflammatory.
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