Cat. No. 0357
Biological ActivityA partial agonist for melatonin receptors in the retina. Also used for determination of serotonin N-acetyl transferase.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Dubocovich (1995) Melatonin receptors: are there multiple subtypes? TiPS 16 50. PMID: 7762083.
Thomas et al (1990) Arylalkylamine (serotonin) N-acetyl transferase assay using high-performance liquid-chromatography with fluorescence or electrochemical detection of N-acetyltryptamine. Anal.Biochem. 184 228. PMID: 2327568.
Dubocovich (1988) Luzindole (NO 774): a novel melatonin receptor antagonist. J.Pharmacol.Exp.Ther. 246 902. PMID: 2843633.
Dubocovich (1985) Characterization of a retinal melatonin receptor. J.Pharmacol.Exp.Ther. 234 395. PMID: 2991499.
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Keywords: N-Acetyltryptamine, supplier, Melatonin, partial, agonists, MT1, MT2, MT3, antagonists, Serotonin, N-acetyltransferase, Substrate, serotonin, N-acetyl, transferase, MT, Receptors, 5-HT3, 5-Hydroxytryptamine, 5-HT, Transferases, activators, Tocris Bioscience, Other Transferase Substrate products
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