SDZ 205-557 hydrochloride

Cat. No. 2037

SDZ 205-557 hydrochloride C14H21ClN2O3.HCl [1197334-02-3]

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Chemical Name: 4-Amino-5-chloro-2-methoxybenzoic acid 2-(diethylamino)ethyl ester hydrochloride

Biological Activity

5-HT3/5-HT4 receptor antagonist.

Technical Data

M.Wt:
337.25
Formula:
C14H21ClN2O3.HCl
Solubility:
Soluble to 100 mM in water
Purity:
>99 %
Storage:
Desiccate at RT
CAS No:
1197334-02-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

McMahon and Cunningham (1999) Antagonism of 5-hydroxytryptamine(4) receptors attenuates hyperactivity induced by cocaine: putative role for 5-hydroxytryptamine(4) receptors in the nucleus accumbens shell. J.Pharmacol.Exp.Ther. 291 300. PMID: 10490917.

Eglen et al (1993) The action of SDZ 205,557 at 5-hydroxytryptamine (5-HT3 and 5-HT4) receptors. Br.J.Pharmacol. 108 376. PMID: 8448587.

Buchheit et al (1992) SDZ 205-557, a selective, surmountable antagonist for 5-HT4 receptors in the isolated guinea pig ileum. Naunyn-Schmied.Arch.Pharmacol. 345 387.

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Keywords: SDZ 205-557 hydrochloride, supplier, 5-HT3/5-HT4, receptors, antagonists, 5-Hydroxytryptamine, 5-HT, SDZ205-557, hydrochloride, Tocris Bioscience, 5-HT4 Receptor Antagonist products

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