XAC

Cat. No. 3200 7 篇引用文献提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

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说明： Adenosine receptor antagonist

别名： Xanthine amine congener

化学名： N-(2-Aminoethyl)-2-[4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]-acetamide dihydrochloride

纯度： ≥98% (HPLC)

引用文献 (7)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for XAC

XAC is an adenosine receptor antagonist (IC₅₀ values are 1.8 and 114 nM at A₁ and A₂ receptors respectively). Attenuates adenosine-induced vasodilation and exhibits proconvulsant activity in vivo.

化合物库 for XAC

XAC is also offered as part of the Tocriscreen 2.0 Max. 了解 Tocris 化合物库的更多信息。

技术数据 for XAC

分子量	501.41
公式	C₂₁H₂₈N₆O₄.2HCl
储存	Desiccate at RT
纯度	≥98% (HPLC)
CAS Number	1962928-23-9
PubChem ID	121513846
InChI Key	KGNTWECSNGWFKE-UHFFFAOYSA-N
Smiles	O=C1N(CCC)C(C(NC(C3=CC=C(OCC(NCCN)=O)C=C3)=N2)=C2N1CCC)=O.Cl.Cl

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for XAC

	溶剂	最高浓度 mg/mL	最高浓度 mM
溶解性
溶解性	DMSO	50.14	100

制备储备液 for XAC

以下数据基于产品分子量 501.41。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

浓度/溶剂体积/质量	1 mg	5 mg	10 mg
1 mM	1.99 mL	9.97 mL	19.94 mL
5 mM	0.4 mL	1.99 mL	3.99 mL
10 mM	0.2 mL	1 mL	1.99 mL
50 mM	0.04 mL	0.2 mL	0.4 mL

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产品说明书 for XAC

分析证书/产品说明书

化学品安全技术说明书

参考文献 for XAC

参考文献是支持产品生物活性的出版物。

Morgan et al (1989) Potent convulsant actions of the adenosine receptor antagonist, xanthine amine congener (XAC) Life Sci. 45 719 PMID: 2779359

Sawmiller et al (1994) Effects of xanthine amine congener on hypoxic coronary resistance and venous and epicardial adenosine concentrations. Cardiovasc.Res. 28 604 PMID: 8025903

Wei beta and Grisshammer (2002) Purification and characterization of the human adenosine A_2A receptor functionally expressed in Escherichia coli. Eur.J.Biochem. 269 82 PMID: 11784301

If you know of a relevant reference for XAC, please let us know.

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关键词: XAC, XAC supplier, adenosine, receptors, antagonists, A1, A2, non-selective, xanthene, amine, congener, Xanthine, Non-selective, Adenosine, 3200, Tocris Bioscience