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Displaying products by catalog number (4800 - 4899)

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Cat.No.
Product Name / Activity
48004EGI-1

Inhibitor of eIF4E:eIF4G interaction

4801QNZ 46

NR2C/NR2D-selective NMDA receptor non-competitive antagonist

4803CRANAD 2

Near-infrared probe that detects Aβ40 aggregates

4804APETx2

ASIC3 channel blocker

4805TCS HDAC6 20b

Selective HDAC6 inhibitor

4806BMS 345541

Selective allosteric inhibitor of IKK; anti-inflammatory

4808FK 866 hydrochloride

Non-competitive and potent NAMPT inhibitor; induces apoptosis and autophagy

4809DSR 6434

Potent TLR7 agonist

4810BAM 7

Selective Bax activator; induces Bax-mediated apoptosis

4811TAT 14

Nrf2 pathway activator; blocks Nrf2/Keap1 interaction

4812ADWX 1

Potent and selective KV1.3 channel blocker

4813Paprotrain

Reversible inhibitor of MKLP-2

4814Methoxyresorufin

Fluorometric CYP450 substrate

48153-Cyano-7-ethoxycoumarin

Fluorescent cytochrome P450 substrate

4816Pentoxyresorufin

Fluorometric cytochrome P450 substrate

4817SKPin C1

Inhibits Skp2-mediated p27 degradation; induces cell cycle arrest

4818PF 04418948

Potent and selective EP2 receptor antagonist

4819Methylprednisolone

Glucocorticoid receptor agonist

4820PF 04691502

Potent and selective dual PI 3-K/mTOR inhibitor

4821PF 03814735

Aurora kinase A and B inhibitor

4822Clindamycin hydrochloride

Antibiotic; inhibits protein synthesis

4823PF 05212384

Potent and selective dual PI 3-K/mTOR inhibitor

4824PD 334581

MEK1 inhibitor

4825TC ASK 10

Potent and selective ASK1 inhibitor; orally bioavailable

4826SUN 11602

Basic fibroblast growth factor (bFGF) mimetic; neuroprotective

4827Garcinol

PCAF/p300 inhibitor; anticancer

4828LDN 209929 dihydrochloride

Potent and selective haspin inhibitor

4829ML 239

Breast cancer stem cell inhibitor

4830LMK 235

Selective HDAC4/HDAC5 inhibitor

4831NS 3861

α3β2 full agonist; also α3β4 partial agonist

4832AZ 12216052

Positive allosteric modulator at mGlu8

4833Levonorgestrel

Synthetic progesterone analog

4835GPP 78 hydrochloride

NAMPT inhibitor; also induces autophagy

4836AZ 628

Potent Raf kinase inhibitor

4837AZD 3988

Potent and selective DGAT-1 inhibitor

4838AZ 12080282 dihydrochloride

Inhibitor of Hedgehog (Hh) signaling

4839AZD 6482

Potent and selective PI 3-Kβ inhibitor

4840KU 0060648

Dual DNA-PK and PI 3-K inhibitor

4842BIX 02189

Selective MEK5 and ERK5 inhibitor

4844HJC 0350

Selective Epac2 inhibitor

4845A 939572

Potent SCD-1 inhibitor

4846Apicidin

Potent histone deacetylase inhibitor

4847PluriSln 1

SCD-1 inhibitor

4848MI 2 (MALT1 inhibitor)

MALT1 inhibitor

48493-Nitropropionic acid

Irreversible mitochondrial respiratory complex II inhibitor

4852Carbetocin

Oxytocin analog

48538-pCPT-2-O-Me-cAMP-AM

Selective Epac activator; cell-permeable analog of 8CPT-2Me-cAMP (Cat. No. 1645)

4854ML 00253764 hydrochloride

Melanocortin MC4 receptor antagonist; brain penetrant

4855WIKI4

Potent tankyrase inhibitor

4857Amlexanox

Inhibitor of TBK1 and IKKε; antiallergic agent

4858NSC 697923

Selective UBE2N inhibitor

4859ML 202

Pyruvate kinase M2 activator

4860ML 193

Potent, selective GPR55 antagonist

4862PPTN hydrochloride

High affinity and selective P2Y14 antagonist

4863CA 074

Selective cathepsin B inhibitor

4864NS 6180

Potent KCa3.1 channel blocker

4865APY 29

Inhibits IRE1α autophosphorylation; activates IRE1α endoribonuclease activity

4866ML 190

Selective κ opioid receptor antagonist

4868SR 1001

RORα/γ inverse agonist

4869SR 2211

Selective RORγ inverse agonist

4870H2L 5765834

LPA1,3,5 antagonist

4872KML 29

Highly potent and selective MAGL inhibitor

4874SR 1078

RORα/γ agonist

4875Senexin A

Cyclin-dependent kinase 8 (cdk8) inhibitor

4876Eact

Activator of Ca2+-activated Cl- channel transmembrane protein 16A (TMEM16A)

4877CaCCinh-A01

Calcium-activated chloride channel (CaCC) inhibitor

4878H2L5186303

Potent and selective LPA2 receptor antagonist

4879TC-G 1001

GPR35 agonist; more potent than zaprinast (Cat. No. 0947)

4880ML 281

STK33 inhibitor

4881LUF 6283

HCA2 (GPR109A) partial agonist

4883CU CPT 4a

Selective TLR3 inhibitor

4884CU CPT 22

Selective TLR1/2 inhibitor

4885R 1530

Multi-RTK inhibitor; inhibits angiogenesis

4886RU-SKI 43 hydrochloride

Hedgehog acyltransferase (Hhat) inhibitor; cell permeable

4887OAC-1

Oct4 activator; enhances iPSC reprogramming efficiency

4888KHS 101 hydrochloride

Selective inducer of neuronal differentiation in hippocampal neural progenitors

4889SGC-CBP30

Potent CBP/p300 BRD inhibitor

4890AR-C 118925XX

Selective, competitive P2Y2 receptor antagonist

4891I-CBP 112

Selective CBP/p300 BRD inhibitor

4892(R)-PFI 2 hydrochloride

Potent and selective SETD7 inhibitor

4893XL 388

Potent and selective mTOR inhibitor; antitumor

4895ML 298 hydrochloride

Selective PLD2 inhibitor

4896LH 846

Selective casein kinase 1δ inhibitor

4897CYM 5541

Selective S1P3 receptor allosteric agonist

4898TC-E 5006

γ-secretase modulator; reduces Aβ42 levels

4899ML 120B dihydrochloride

Novel IKK2-selective inhibitor

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