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Displaying products by catalog number (4500 - 4599)

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Product Name / Activity

Potent Mnk2 inhibitor


Antiviral guanosine analog; blocks eIF4E activity


Activates Chk2; induces G2/M cell cycle arrest

4503CC 0651

Allosteric inhibitor of hCdc34


SUV39H1 inhibitor

4505ICG 001

Inhibits TCF/β-catenin-mediated transcription

4506TAME hydrochloride

Ubiquitin ligase APC/C inhibitor; promotes Cdc20 autoubiquitination

4507ML 218 hydrochloride

Ca2+ channel blocker (T-type)

4508S 32212 hydrochloride

5-HT2C inverse agonist; α2 antagonist

4509STF 083010

Inhibits IRE1α endonuclease activity

4510SHA 68

Selective neuropeptide S receptor antagonist


Activator of Nrf2 pathway; primary metabolite of DMF (Cat. No. 4512)


Nrf2 pathway activator; neuroprotective


Potently induces chondrogenesis in MSCs

4514JW 55

Tankyrase inhibitor


Non-metabolizable glucose analog; hexokinase substrate

4516UNC 926 hydrochloride

L3MBTL1 domain inhibitor

4517NS 2028

Potent soluble guanylyl cyclase (sGC) inhibitor


Trace amine 1 (TA1) receptor antagonist/inverse agonist

4519ML 213

KV7.2 and KV7.4 channel opener


Nucleoside analog; inhibits DNA replication

4521TAS 301

Inhibitor of smooth muscle cell migration and proliferation

4522Flufenamic acid

Calcium-activated chloride channel blocker; NSAID. Also activates TRPC6


Chloride channel blocker; TRPV1 modulator; RAD51 recombinase inhibitor


Inhibits formation of amyloid fibrils


Potent and selective PDE4 inhibitor

4527TC-I 15

Potent α2β1 inhibitor; displays antithrombotic activity in vivo

4528(±)-NBI 74330

Potent and selective CXCR3 antagonist

4529Ciliobrevin A

Hedgehog (Hh) pathway antagonist, inhibits ciliogenesis; also inhibits dynein

4530ONO 2506

Inhibits S-100β synthesis; neuroprotective

4531NCX 4040

NO-donating aspirin; anti-inflammatory and antitumor

4532VUF 10166

High affinity 5-HT3 receptor antagonist

4533PTAC oxalate

Muscarinic receptor ligand; exhibits partial agonist and antagonist activity at different subtypes

4534CZC 54252 hydrochloride

Potent LRRK2 inhibitor; neuroprotective


Promotes actin polymerization


Toll-like receptor 7 (TLR7) agonist

4537NCX 466

Cyclooxygenase-inhibiting nitric oxide donor

4538T16Ainh - A01

Ca2+-activated Cl- channel transmembrane protein 16A (TMEM16A) inhibitor

4539(R)-(+)-Etomoxir sodium salt

Carnitine palmitoyltransferase I (CPT1) inhibitor

4540U 104

Potent carbonic anhydrase (CA) IX and XII inhibitor

4541SGC 0946

Highly potent and selective DOT1L inhibitor; cell permeable


High affinity FP prostaglandin receptor agonist

4543CS 2100

Selective S1P1 agonist

4544YM 244769

Na+/Ca2+ exchange inhibitor (reverse mode); neuroprotective

4545E 64d

Cathepsin inhibitor; interferes with autolysosomal digestion

4546rac-CCT 250863

Potent Nek2 inhibitor


Selective IKKα and IKKβ inhibitor

4549ML 133 hydrochloride

Kir2 channel blocker

4550IQ 3

Selective JNK3 inhibitor


Smo receptor agonist

4552A 412997 dihydrochloride

Selective D4 agonist


Potent AT1 receptor inverse agonist; antihypertensive

4554GC 1

High affinity thyroid receptor α (TRα) and TRβ agonist; thyromimetic

4555HI TOPK 032

Selective T-LAK-cell-originated protein kinase (TOPK) inhibitor

4556CP 690550 citrate

Potent JAK inhibitor

4557GTS 21 dihydrochloride

Partial agonist at α7 nAChR


Highly potent and selective OX2 antagonist; brain penetrant

4559GNF 5837

Potent Trk inhibitor; inhibits TrkA, TrkB and TrkC

4561BIBN 4096

Potent and selective CGRP receptor antagonist

4562Topotecan hydrochloride

DNA topoisomerase I inhibitor; Camptothecin (Cat. No. 1100) analog

4564JTV 519 fumarate

Ryanodine receptor (RyR) inhibitor

4565ML 228

HIF pathway activator

4566NSC 687852

Inhibitor of UCHL5 and USP14

4567CCG 50014

Potent and selective inhibitor of regulator of G-protein signaling 4 (RGS4) protein


DOCK2-Rac1 interaction inhibitor

4569PS 1145 dihydrochloride

Selective IKK inhibitor; orally active

4570ML 161

Inhibits PAR1-mediated platelet activation

4571A 867744

Positive allosteric modulator of α7 nAChR

4572TC-E 5005

Potent and selective PDE10A inhibitor

4574ARN 272

FAAH-like anandamide transporter (FLAT) inhibitor

4575TC HSD 21

Potent and selective 17β-hydroxysteroid dehydrogenase type 3 inhibitor


Fluorescent ligand for α4β1 (VLA-4)

4578Phenobarbital sodium salt

Enhances GABAergic activity

4579Pentobarbital sodium salt

Enhances GABAergic activity

4580Atiprimod dihydrochloride

JAK2 inhibitor

4581Grifolic acid

Selective partial FFA4 (GPR120) agonist

4582MLR 1023

Selective allosteric activator of Lyn kinase


Na+/K+ ATPase inhibitor

4584SNS 314 mesylate

Potent pan-Aurora kinase inhibitor

4585MRT 10

Smoothened (Smo) antagonist

4586ML 3403

p38 inhibitor


Potent equilibrative nucleoside transporter (ENT) inhibitor


Blocks NF-κB activation; also anti-inflammatory and antioxidant

4591Deltorphin I

Potent δ agonist


Pim-1 kinase inhibitor

4593GSK J1

Potent JMJD3/UTX inhibitor

4594GSK J4

Histone KDM inhibitor; cell permeable

4596IT1t dihydrochloride

Potent CXCR4 antagonist

4597NS 8593 hydrochloride

Selective KCa2 (SK) channel negative modulator; inhibits SK currents

4598PHT 427

Dual Akt and PDK1 inhibitor; antitumor


Selective HCA1 agonist

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