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Displaying products by catalog number (4400 - 4499)

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Product Name / Activity
4400(±)-CPSI 1306

Reported macrophage migration inhibitory factor (MIF) inhibitor


FH2 domain inhibitor; prevents actin nucleation


Ligand of GPR103; orexigenic neuropeptide


Histone deacetylase inhibitor

4404VU 0365114

Positive allosteric modulator of M5 receptors

4405NVP BHG 712

Potent EphB4 kinase inhibitor


Inhibits c-Myc-Max dimerization

4407TC-G 1004

Potent and selective A2A antagonist


Prolyl hydroxylase inhibitor

4409SR 1664

High affinity PPARγ ligand; blocks Cdk5-dependent PPARγ phosphorylation


GABAA modulator; anxiolytic


Non-selective serotonin receptor agonist

4414TP 003

Functionally selective GABAA receptor (α3 subtype) partial agonist

4415MK 0343

Subtype-selective GABAA receptor partial agonist

4416ADX 10059 hydrochloride

Negative allosteric modulator at mGlu5


Selective and reversible p97 ATPase inhibitor

4418Saquinavir mesylate

HIV protease inhibitor

4419PF 945863

Macrolide antibiotic

4420Carbazeran citrate

Aldehyde oxidase substrate; PDE inhibitor

4421LF 11

Antibiotic; neutralizes LPS

4422Lauryl-LF 11

Analog of LF 11 (Cat. No. 4421); antibiotic

4423CHIR 99021

Highly selective GSK-3 inhibitor

4424SR 16584

Selective α3β4 nAChR antagonist

4426Tanshinone IIA

Inhibits NF-κB and AP-1 DNA binding. Displays antioxidant properties


Xanthine oxidase inhibitor


Fluorescent mitochondrial hydrogen peroxide indicator

4429NQDI 1

ASK1 inhibitor

4430BAY 41-2272

Soluble guanylyl cyclase (sGC) activator

4431A 1070722

Highly potent, selective GSK-3 inhibitor

4432TTP 22

High affinity, selective CK2 inhibitor


Dual ERK1/RasGAP inhibitor. Maintains ESC self-renewal


N-WASP inhibitor; inhibits Arp2/3 activation

4435TC-N 1752

NaV channel blocker


Cytotoxic nucleoside analog; inhibits RNA synthesis

4437VU 0357121

Positive allosteric modulator of mGlu5

4438MFZ 10-7

Negative allosteric modulator at mGlu5

4439ISX 9

Neurogenic agent; induces neuronal differentiation of SVZ progenitors and also induces cardiomyogenic differentiation

4440Rivastigmine tartrate

Dual AChE and BChE inhibitor

4441SEN 12333

α7 nAChR agonist; histamine H3 antagonist

4443Mephedrone hydrochloride

Inhibits synaptosomal dopamine and 5-HT uptake

4444Fatostatin A

Cell permeable inhibitor of SREBP activation

4445PFI 1

BET bromodomain inhibitor

4446CID 5951923

Krüppel-like factor 5 (KLF5) inhibitor

4447Org 24598

Inhibitor of GlyT1; derivative of Org 24598 (Cat. No. 4035).

4448Ceranib 1

Ceramidase inhibitor; antiproliferative

4451IOX 2

Potent, selective HIF-1α prolyl hydroxylase-2 (PHD2) inhibitor


Inhibitor of γ-glutamyl transpeptidase (GGT)

4453GDC 0879

Potent B-Raf inhibitor

4454Diclofenac sodium salt

Cyclooxygenase inhibitor; NSAID


ACE inhibitor; also inhibits LTA4 hydrolase

4456Amitriptyline hydrochloride

5-HT and noradrenalin re-uptake inhibitor; also TrkA/B agonist

4457YE 120

GPR35 agonist

4458VU 29

Potent mGlu5 allosteric potentiator

4459TC-S 7005

Potent and selective PLK2 inhibitor


Thymidylate synthase inhibitor; induces DNA fragmentation

4462NS 3623

KV11.1 (hERG) and KV4.3 channel activator; antiarrhythmic

4463SR 8278

Rev-Erbα antagonist

4464IOX 1

Histone demethylase inhibitor; cell permeable

4465TCS ERK 11e

Potent and selective ERK2 inhibitor

4466PHP 501 trifluoroacetate

Potent GABAA antagonist

4468AT 1015

Long-acting 5-HT2A antagonist

4469VU 0364770

Positive allosteric modulator at mGlu4

4470EMD 281014 hydrochloride

Selective 5-HT2A antagonist


Selective VEGFR-2 inhibitor

4472BAY 60-6583

Potent A2B receptor agonist; cardioprotective

4473A 804598

Potent and selective P2X7 antagonist


Allosteric activator of Hedgehog (Hh) signaling; induces Smo accumulation

4475Cardionogen 1

Inhibitor of Wnt/β-catenin signaling

4477A 844606

Selective α7 nAChR partial agonist


GPBA receptor (TGR5) agonist


Inhibits IRE1α endoribonuclease activity

4480DV 7028 hydrochloride

Selective 5-HT2A antagonist; antithrombotic

4481Ki 20227

c-Fms inhibitor; suppresses osteolysis and osteoclast accumulation

4482PR 619

Broad spectrum DUB inhibitor

4483A 484954

CaM kinase III (eEF-2 kinase) inhibitor

4484STF 31

NAMPT inhibitor; also GLUT1 inhibitor

4485P 22077

USP7 inhibitor


Non-selective protease inhibitor; also blocks anandamide metabolism

4487(±)-AMG 487

CXCR3 antagonist; inhibits cell migration and metastasis


Adenosine deaminase inhibitor


γ-secretase inhibitor; inhibits Notch pathway


Antiproliferative; induces activin/Smad3 signaling

4491DQP 1105

Selective NR2C/NR2D receptor antagonist


Potent and noncompetitive NMDA receptor antagonist


Atypical antipsychotic; 5-HT2A and D2 antagonist


Enantiomer of DPN (Cat. No. 1494)


γ-secretase inhibitor; lowers Aβ42 levels in vitro

4496BC 11-38

Selective PDE11 inhibitor

4498Y 11

Potent and selective FAK inhibitor


Potent, selective BET bromodomain inhibitor; cell permeable

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SENC 2017

17th National Congress of the Spanish Society of Neuroscience

September 27 - 30, 2017

Alicante, Spain