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Displaying products by catalog number (2100 - 2199)

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Product Name / Activity

Selective D2/D3 receptor antagonist; atypical antipsychotic agent


α7 subtype-selective nAChR antagonist

2134Salvinorin A

Highly potent and selective κ agonist

21372,3-DCPE hydrochloride

Selectively induces cancer cell apoptosis

2138Xenin 8

Neurotensin-like peptide; potentiates insulin and glucagon secretion

2139Leelamine hydrochloride

CB1 agonist

2141Paroxetine maleate

Highly potent and selective 5-HT uptake inhibitor

2142[Ala11,D-Leu15]-Orexin B

Potent, selective OX2 receptor agonist


Selective GABAA receptor antagonist; β1-subunit-selective


Inhibitor of 14.3.3 proteins


High affinity inhibitor of 14.3.3 proteins; induces apoptosis

2146MRS 2578

Selective P2Y6 antagonist


Kir6 (KATP) channel opener and NO donor

2148(±)-McN 5652

Potent, orally active 5-HT uptake inhibitor. Also inhibits noradrenalin and dopamine uptake in vitro


Potent, selective PPARγ partial agonist


Selective inhibitor of Akt/PKB signaling. Antitumor and antiviral

2152NSC 625987

Cyclin-dependent kinase 4 (cdk4) inhibitor

2154ZD 2079

β3-adrenoceptor agonist

2155NTNCB hydrochloride

Potent and selective non-peptidic NPY Y5 antagonist


Inhibitor of X-linked inhibitor of apoptosis (XIAP); cell-permeable and antitumor

2157MRS 2365

Highly potent and selective P2Y1 agonist

2158MRS 2279

Selective, high affinity P2Y1 antagonist

2159MRS 2500 tetraammonium salt

Extremely potent and selective P2Y1 antagonist

2160Bax channel blocker

Inhibits Bax-mediated mitochondrial cytochrome c release

2161NSC 23766

Selective inhibitor of Rac1-GEF interaction; antioncogenic


Inhibitor of calcineurin-substrate association


Cell-permeable, irreversible caspase inhibitor


Cell-permeable, irreversible caspase-3 inhibitor


Caspase-3 inhibitor

2172AZ 10417808

Selective non-peptide caspase-3 inhibitor

2173WAY 629 hydrochloride

Selective 5-HT2C agonist


Partial positive allosteric modulator at the benzodiazepine receptor


Potent inhibitor of vesicular monoamine transport

2176BVT 948

Non-competitive protein tyrosine phosphatase inhibitor; enhances insulin signaling

2177BVD 10

Highly selective NPY Y1 receptor antagonist; devoid of Y4 agonist activity

2181Vanilloid TRPV1 Receptor Tocriset™

Selection of 5 vanilloid TRPV1 receptor ligands (Cat. Nos. 0462, 0934, 1137, 0464 and 1615)

2183ZK 164015

Potent estrogen receptor antagonist


Selective Na+/Ca2+ exchange inhibitor (reverse mode)

2185NSC 146109 hydrochloride

Cell-permeable, genotype-selective antitumor agent; activates p53-dependent transcription


Selective inhibitor of p38α-mediated MK2a phosphorylation; also tubulin polymerization inhibitor

2187NS 3763

Selective non-competitive kainate antagonist; selective for GLUK5

2188Ro 0437626

Selective P2X1 antagonist

2190SR 27897

Potent and selective CCK1 antagonist


Potent, selective inhibitor of mitotic kinesin Eg5


PARP inhibitor

2193Carmoxirole hydrochloride

Selective, peripherally acting D2-like agonist

2194R 59-022

Diacylglycerol kinase inhibitor; increases PKC activity


Non-competitive NR2B-selective NMDA antagonist


Potent, selective mGlu1 antagonist


Very potent and selective β3 partial agonist

2198Mibefradil dihydrochloride

Ca2+ channel blocker (T-type)

2199CGP 71683 hydrochloride

Highly selective and potent non-peptide NPY Y5 receptor antagonist

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Careers at Tocris

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November 8 - 10, 2017

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