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Displaying products alphabetically by name (N)

Product Name / Activity

Activator of SUMO-activating enzyme, E1 ligase

2213N20C hydrochloride

Non-competitive NMDA receptor open-channel blocker

3905NAADP tetrasodium salt

Ca2+ mobilizing agent

5131NAB 2

Protects against α-synuclein toxicity; promotes Rsp5/Nedd4-dependent endosomal transport

3282NAD 299 hydrochloride

Selective, high affinity 5-HT1A antagonist


Endogenous CB1 agonist. Also vanilloid agonist and inhibitor of FAAH and AMT

5515NADPH reduced form tetrasodium salt

Cofactor for many anabolic enzymes


Highly potent, preferential D3 antagonist

3081Nafamostat mesylate

Serine protease inhibitor, inhibits tryptase


GnRH receptor agonist

0597Naftopidil hydrochloride

α1 antagonist

4085Nalmefene hydrochloride

Opioid receptor antagonist

3971Nalmefene - d3

Deuterated nalmefene; opioid receptor antagonist

0591Naloxonazine dihydrochloride

Selective μ1 antagonist

0599Naloxone hydrochloride

Broad spectrum opioid antagonist

5684Naloxone 3-glucuronide carbonic acid salt

Naloxone conjugate

1419Naloxone benzoylhydrazone

Full κ agonist, partial μ and δ agonist and antagonizes agonist-induced activation of NOP

0677Naltrexone hydrochloride

Broad spectrum opioid antagonist

0892Naltriben mesylate

Standard δ2 selective antagonist

0740Naltrindole hydrochloride

Selective non-peptide δ antagonist

0665L-NAME hydrochloride

Non-selective NOS inhibitor

0553NAN-190 hydrobromide

5-HT1A antagonist


STAT3 inhibitor; also blocks cancer stem cell self-renewal

30631-Naphthyl PP1

Src family kinase inhibitor; also inhibits c-Abl

2655Naproxen sodium

Cyclooxygenase inhibitor


Antiproliferative agent; slows cell cycle progression


Selective r5-HT1B antagonist. Active in vivo

2766Naspm trihydrochloride

Ca2+-permeable AMPA receptor antagonist


Kir6 (KATP) blocker; displays high affinity for SUR1/Kir6.2 channels

4691NAV 26

Selective Nav1.7 channel blocker

5811NBD 556

CD4 mimetic; blocks HIV-1 cell entry

1591NBI 27914 hydrochloride

Selective non-peptide CRF1 antagonist

5192NBI 31772

High affinity insulin-like growth factor-I binding protein IGFBP inhibitor

3100NBI 35965 hydrochloride

Potent and selective CRF1 antagonist

4528(±)-NBI 74330

Potent and selective CXCR3 antagonist


Equilibrative nucleoside transporter 1 (ENT1) inhibitor

5171NBOH-2C-CN hydrochloride

High affinity, selective 5-HT2A agonist


Potent AMPA antagonist. More selective than CNQX (Cat. No. 0190)

1044NBQX disodium salt

Potent AMPA antagonist. More water soluble form of NBQX (Cat. No. 0373)

3747NCH 51

Histone deacetylase inhibitor


Antagonist of γ-hydroxybutyric acid

4531NCX 4040

NO-donating aspirin; anti-inflammatory and antitumor

4537NCX 466

Cyclooxygenase-inhibiting nitric oxide donor

3333NDT 9513727

Potent, selective human C5a receptor antagonist

3133NE 100 hydrochloride

Selective σ1 antagonist

3517Nebivolol hydrochloride

Highly selective β1-adrenoceptor antagonist


High affinity adenosine receptor agonist


RIPK1 inhibitor; inhibits necroptosis


Necroptosis inhibitor

3953cis-Ned 19

NAADP antagonist; inhibits Ca2+ release

3954trans-Ned 19

NAADP antagonist; inhibits Ca2+ release

2777Nefazodone hydrochloride

5-HT2A antagonist and 5-HT uptake inhibitor. Antidepressant


Cognitive enhancer

3766Nelfinavir mesylate

Potent HIV-1 protease inhibitor


Highly potent D2-like antagonist. Also 5-HT1A agonist


Stimulated by IFN-γ; marker of immune activation

5037Nepicastat hydrochloride

Potent and selective dopamine β-hydroxylase (DBH) inhibitor; orally bioavailable


Induces neurogenesis in mature skeletal muscle cells

1152Neurokinin A (porcine)

Endogenous tachykinin peptide

1640[bAla8]-Neurokinin A(4-10)

NK2 agonist

1582Neurokinin B (human, porcine)

Endogenous tachykinin peptide

1908Neuromedin B (porcine)

Mammalian bombesin-like peptide

1907Neuromedin N (rat, mouse, porcine, canine)

Neurotensin-like peptide

3648Neuromedin S (rat)

Potent, endogenous NMU1 and NMU2 agonist

1917Neuromedin U (rat)

Endogenous modulator of blood pressure and flow, gut ion transport, feeding and body temperature


Selective inducer of neuronal differentiation in hippocampal neural progenitors

1928Neuropeptide AF (human)

Implicated in pain modulation, opioid function and metabolism

3137Neuropeptide FF

Endogenous NPFF1 and NPFF2 agonist

2587Neuropeptide S (human)

Potent endogenous neuropeptide S receptor agonist

5857Neuropeptide S (Mouse)

Potent endogenous neuropeptide S receptor (NPSR) agonist

5859Neuropeptide S (Rat)

Potent endogenous neuropeptide S receptor agonist

3647Neuropeptide SF (mouse, rat)

NPFF1 and NPFF2 agonist

3009Neuropeptide W-23 (human)

Endogenous NPBW1 and NPBW2 receptor agonist

3903Neuropeptide Y (scrambled)

Control peptide for neuropeptide Y (Cat. No. 1173)

1177Neuropeptide Y 13-36 (porcine)

NPY Y2 receptor agonist

1153Neuropeptide Y (human, rat)

Influences feeding and sexual behavior

1173Neuropeptide Y (porcine)

Influences feeding and sexual behavior

3436[D-Trp34]-Neuropeptide Y

Potent NPY Y5 agonist; orexigenic

1176[Leu31,Pro34]-Neuropeptide Y (human, rat)

NPY Y1 receptor agonist

1168[Leu31,Pro34]-Neuropeptide Y (porcine)

NPY Y1 receptor agonist

5905Neurosensor 521

Selective noradrenalin and dopamine fluorescent indicator


Endogenous neurotransmitter and endocrine modulator

1240NF 023

Selective, competitive P2X1 antagonist

2548NF 110

Potent P2X3 antagonist

2450NF 157

Selective P2Y11/P2X1 antagonist

1199NF 279

Potent and selective P2X1 antagonist

3830NF 340

Selective P2Y11 antagonist

1391NF 449

Highly selective P2X1 antagonist

3892NF 546

Selective P2Y11 agonist

3930NFAT Inhibitor

Inhibitor of calcineurin-mediated NFAT activation

5710NFAT inhibitor, Cell Permeable

Cell permeable NFAT inhibitor


Selective non-transportable GlyT1 inhibitor

5429NG 25

TGF-β-activated kinase (TAK1) inhibitor

2635NGB 2904

Potent and selective D3 antagonist

3298NGD 94-1

Selective D4 receptor ligand

4315NGD 98-2 hydrochloride

High affinity CRF1 antagonist

3439NH 125

CaM kinase III (eEF-2 kinase) inhibitor

5363NHI 2

LDHA inhibitor

5786NI 42

High affinity BRPF inhibitor

5546NI 57

Potent and selective BRPF bromodomain inhibitor

5203NIBR 189

Potent and selective EBI2 (GPR183) receptor antagonist


α antagonist


STAT3 inhibitor; also inhibits mTORC1 signaling


Kir6 (KATP) channel opener and NO donor


PARP-1 inhibitor

3546(-)-Nicotine ditartrate

Prototypical nAChR agonist

3921NIDA 41020

High affinity CB1 antagonist


Ca2+ channel blocker (L-type)

4112Niflumic acid

Cyclooxygenase-2 (COX-2) inhibitor; GPR35 agonist

4312Nigericin sodium salt

Selective K+ ionophore

1124(R)-(-)-Niguldipine hydrochloride

α1 antagonist, L-type Ca2+ channel blocker. Less active enantiomer of Niguldipine hydrochloride (Cat. No. 1123)

1123(S)-(+)-Niguldipine hydrochloride

α1 antagonist, L-type Ca2+ channel blocker

1139L-NIL hydrochloride

Selective iNOS inhibitor


Androgen receptor antagonist. Orally active


Syk kinase inhibitor; inhibits Aβ production


Cyclooxygenase-2 (COX-2) inhibitor


Ca2+ channel blocker (L-type)


Non-selective NOS inhibitor. Sodium salt of 7-nitroindazole (Cat. No. 0602)

0546L-NIO dihydrochloride

NOS inhibitor

0236(±)-Nipecotic acid

GABA uptake inhibitor

1025Nisoxetine hydrochloride

Noradrenalin re-uptake inhibitor


Ca2+ channel blocker (L-type)

0469Nitrocaramiphen hydrochloride

Muscarinic antagonist, M1 > M2


Non-selective NOS inhibitor

48493-Nitropropionic acid

Irreversible mitochondrial respiratory complex II inhibitor

5293NK 252

Nrf2 activator


Selective NK2 agonist

1603NKH 477

Water-soluble adenylyl cyclase activator

5071NKY 80

Adenylyl cyclase inhibitor


Selective NMDA agonist

1823NMDA Receptor - Glycine Site Tocriset™

Selection of 5 NMDA receptor (glycine site) ligands (Cat. Nos. 0219, 0281, 0742, 1493 and 0237)

0771L-NMMA acetate

Non-selective NOS inhibitor


NOS inhibitor (nNOS = eNOS >> iNOS)

2747NNC 05-2090 hydrochloride

GABA uptake inhibitor; moderately BGT-1 selective

2440NNC 26-9100

Selective sst4 agonist

2268NNC 55-0396 dihydrochloride

Highly selective Ca2+ channel blocker (T-type)

1780NNC 63-0532

Potent non-peptide NOP agonist; brain penetrant

1779NNC 711

Selective inhibitor of GAT-1


Endogenous NOP agonist

1358Nociceptin (1-13)NH2

Potent ORL1 agonist

1266Nociceptin (1-7)

Bioactive metabolite of nociceptin


Highly potent and selective NOP agonist


Potent, selective nociceptin receptor agonist


Selective, competitive nociceptin antagonist


Selective nociceptin receptor agonist


Orphan neuropeptide

1118Nocistatin (bovine)

Opposes action of nociceptin

1198Nocistatin (human)

Human putative counterpart of nocistatin


Microtubule inhibitor

1984Nogo-66 (1-40)

Competitive antagonist for Nogo-66 receptor; promotes neuron regeneration

1411Noladin ether

Endogenous agonist for CB1 and GPR55


Potent noradrenalin and dopamine uptake inhibitor. Antidepressant


Monovalent cation ionophore


Glucosidase inhibitor

09015-Nonyloxytryptamine oxalate

Selective 5-HT1B agonist

5169Noradrenaline bitartrate

Endogenous adrenergic hormone and neurotransmitter

1970Norketamine hydrochloride

Potent, non-competitive NMDA antagonist


Highly potent HGF/c-MET inhibitor; also AT4 antagonist

1697Noscapine hydrochloride

Tubulin inhibitor; induces apoptosis


Orally active AT2 agonist


Potent and selective NADPH oxidase 1 (NOX1) inhibitor

0675NPC 15199

Increases intracellular Ca2+ levels


Caged fluorescent pH indicator


Caged proton


Caged (1S,3R)-ACPD


Caged (S)-3,4-DCPG


Caged (S)-AMPA


Caged D-AP5 (Cat.No. 0106)


Caged dopamine

3332NPEC-caged-LY 379268

Caged group II mGlu receptor agonist


Caged noradrenalin


Caged serotonin


Inhibits calcium-sensitive chloride currents

3626NPS 2143 hydrochloride

Selective antagonist of the calcium-sensing receptor; orally active calcilytic agent

4134NPS 2390

Group I mGlu antagonist

3285NPS ALX Compound 4a dihydrochloride

Potent and selective 5-HT6 antagonist

3677NPY 5RA972

Potent and selective NPY Y5 antagonist

4429NQDI 1

ASK1 inhibitor


Potent inhibitor of Aβ oligomer and fibril formation

4788NS 11021

Activator of BKCa (KCa1.1) channels

3804NS 1619

Activator of BKCa (KCa1.1) channels

3062NS 1643

KV11.1 (hERG) channel activator; antiarrhythmic

2995NS 1738

Positive allosteric modulator of α7 nAChR; active in vivo

5276NS 19504

Activator of BKCa (KCa1.1) channels

4517NS 2028

Potent soluble guanylyl cyclase (sGC) inhibitor

3895NS 309

Positive modulator of KCa2 and KCa3.1 channels

4462NS 3623

KV11.1 (hERG) channel activator; antiarrhythmic

2187NS 3763

Selective non-competitive kainate antagonist; selective for GLUK5

4831NS 3861

α3β2 full agonist; also α3β4 partial agonist

0942NS 398

Cyclooxygenase-2 (COX-2) inhibitor

4166NS 5806

KV4.3 channel activator

4864NS 6180

Potent KCa3.1 channel blocker

4597NS 8593 hydrochloride

Selective KCa2 (SK) channel negative modulator; inhibits SK currents

5112NS 9283

Positive allosteric modulator of α4β2

3034NSC 109555 ditosylate

Selective Chk2 inhibitor

2185NSC 146109 hydrochloride

Cell-permeable, genotype-selective antitumor agent; activates p53-dependent transcription

2161NSC 23766

Selective inhibitor of Rac1-GEF interaction; antioncogenic

5065NSC 319726

Reactivator of mutant p53

4338NSC 33994

JAK2 inhibitor

2521NSC 3852

Histone deacetylase inhibitor

4902NSC 405020

Inhibitor of MT1-MMP; antitumor

5340NSC 617145

Werner syndrome helicase (WRN) inhibitor

4993NSC 624206

Ubiquitin-activating enzyme (E1) inhibitor

2152NSC 625987

Cyclin-dependent kinase 4 (cdk4) inhibitor

2647NSC 632839 hydrochloride

Inhibitor of ubiquitin isopeptidase activity

5287NSC 636819

KDM4A/KDM4B inhibitor

1867NSC 663284

Potent, selective Cdc25 phosphatase inhibitor

2936NSC 66811

MDM2 antagonist. Disrupts MDM2-p53 interaction

4566NSC 687852

Inhibitor of UCHL5 and USP14

1937NSC 693868

Cdk inhibitor. Also inhibits GSK-3

4858NSC 697923

Selective UBE2N inhibitor

4655NSC 74859

Selective STAT3 inhibitor

2613NSC 87877

Potent inhibitor of shp2 and shp1 PTP

1547NSC 95397

Selective Cdc25 dual specificity phosphatase inhibitor

2155NTNCB hydrochloride

Potent and selective non-peptidic NPY Y5 antagonist

2087NTR 368

p75NTR fragment; induces apoptosis

5438NTRC 824

Potent and selective non-peptide NTS2 antagonist


Potent, selective PPARγ partial agonist

1401NU 1025

Potent PARP inhibitor

3135NU 2058

Cdk1 and cdk2 inhibitor

3301NU 6140

Cyclin-dependent kinase 2 (cdk2) inhibitor

2828NU 7026

Selective DNA-PK inhibitor

3712NU 7441

Potent and selective DNA-PK inhibitor

4903NU 9056

Inhibitor of KAT5 (Tip60)


MDM2 antagonist; inhibits MDM2-p53 interaction

3960NVP 231

Potent, selective and reversible CerK inhibitor

5247NVP ADW 742

ATP-competitive inhibitor of IGF1R

4405NVP BHG 712

Potent EphB4 kinase inhibitor

5660NVP CXCR2 20

Potent and selective CXCR2 antagonist

3506NVP DPP 728 dihydrochloride

Potent, orally active dipeptidyl peptidase IV (DPP-IV) inhibitor


Potent and selective inhibitor of cat eye syndrome chromosome region, candidate 2 (CECR2)

2067187-1, N-WASP inhibitor

N-WASP inhibitor; inhibits actin assembly

3645NXY 059

Free radical trapping agent; neuroprotectant

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