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Displaying products alphabetically by name (L)

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Cat.No.
Product Name / Activity
3066L 006235

Potent cathepsin K inhibitor

5085L 012 sodium salt

Chemiluminescent ROS and RNS indicator

4013L 760735

High affinity NK1 receptor antagonist

5045L002

p300 inhibitor

2444(1R,1'S,3'R/1R,1'R,3'S)-L-054,264

Potent and selective sst2 agonist

1382L-152,804

Potent, selective non-peptide NPY Y5 receptor antagonist

2514L-161,982

Selective EP4 receptor antagonist

1856L-165,041

Potent PPARδ agonist

2311L-168,049

Potent, orally active human glucagon receptor antagonist

3561L189

DNA ligase I, III and IV inhibitor

2660L-364,373

KV7.1 channel activator, activates IKs

2767L-365,260

Selective CCK2 antagonist

2641L-368,899 hydrochloride

Potent, non-peptide oxytocin receptor antagonist

2410L-371,257

Potent and selective oxytocin receptor antagonist

3086L-651,582

Ca2+ channel blocker

1698L-655,240

Potent, selective thromboxane A2/prostaglandin endoperoxide antagonist

1327L-655,708

Benzodiazepine inverse agonist; selective for α5-containing GABAA receptors

1949L-670,596

Potent, selective thromboxane A2/prostaglandin endoperoxide antagonist

2627L-685,458

Potent and selective γ-secretase inhibitor

0742L-689,560

Very potent NMDA antagonist

0682L-690,488

Cell permeable prodrug of the IMPase inhibitor L-690,330 (Cat. No. 0681)

0681L-690,330

Inositol monophosphatase inhibitor

2261L-692,585

Potent, non-peptide ghrelin receptor agonist

0426L-693,403 maleate

High affinity σ ligand

0781L-694,247

5-HT1D agonist

0705L-701,252

NMDA antagonist, acts glycine site

0907L-701,324

NMDA antagonist; acts at glycine site

2640L-703,664 succinate

Selective 5-HT1D receptor agonist

0868L-732,138

Potent, selective NK1 antagonist

1145L-733,060 hydrochloride

Potent NK1 antagonist

1004L-741,742 hydrochloride

Highly selective D4 antagonist

1003L-741,626

High affinity D2 antagonist

1002L-745,870 trihydrochloride

Highly selective D4 antagonist

2760L-748,337

Selective β3 antagonist

2197L-755,507

Very potent and selective β3 partial agonist

2434L-759,656

Highly selective CB2 agonist

2433L-759,633

High affinity, selective CB2 agonist

3342L-798,106

Potent and highly selective EP3 antagonist

2235L803

Substrate-competitive inhibitor of GSK-3

1979L-803,087 trifluoroacetate

Potent and selective sst4 agonist

2256L803-mts

Selective inhibitor of GSK-3

1980L-817,818

Potent and selective sst5 agonist

3250L-838,417

Subtype-selective GABAA partial agonist

2267Lactacystin

Cell-permeable, potent and selective proteasome inhibitor

1611Lamotrigine

Inhibits glutamate release. Anticonvulsant

2289Lamotrigine isethionate

Inhibits glutamate release. Water-soluble salt of lamotrigine (Cat. No. 1611)

2582Lansoprazole

H+,K+-ATPase inhibitor

1293β-Lapachone

DNA topoisomerase I inhibitor

4757Latanoprost

FP prostaglandin receptor agonist; also exhibits agonist activity at EP1 and EP3 receptors

3973Latrunculin A

Inhibitor of actin assembly and polymerization

0548(±)-Lauroylcarnitine chloride

Intermediate in lipid metabolism

4422Lauryl-LF 11

Analog of LF 11 (Cat. No. 4421); antibiotic

1331Lavendustin A

EGFR, p60c-src inhibitor

2460Lazabemide hydrochloride

Selective MAO-B inhibitor

4294LB 42708

Selective farnesyltransferase (FTase) inhibitor

5592LCB 03-0110 dihydrochloride

Potent c-SRC kinase inhibitor; also inhibits DDR2, BTK and Syk

5631LDN 193188

Inhibitor of phosphatidylcholine transfer protein (PC-TP)

4828LDN 209929 dihydrochloride

Potent and selective haspin inhibitor

5082LDN 212320

Increases EAAT2 expression; neuroprotective

4602LDN 27219

Transglutaminase 2 (TG2) inhibitor; reversible

3998LDN 57444

Ubiquitin C-terminal hydrolase-L1 (UCH-L1) inhibitor

3788L-DOPA

Dopamine precursor

4577LDV FITC

Fluorescent ligand for α4β1 (VLA-4)

2021LE 135

Selective RARβ antagonist

1674LE 300

Potent and selective dopamine D1 antagonist

2139Leelamine hydrochloride

CB1 agonist

2228Leflunomide

Dihydroorotate dehydrogenase inhibitor

1575Ac-LEHD-AFC

Fluorogenic caspase substrate

5571Lei-Dab 7

High affinity, selective KCa2.2 blocker

2985LEP (116-130) (mouse)

Synthetic leptin peptide fragment

1987Leptomycin B

Inhibits nuclear export of proteins; antitumor

2959Lercanidipine hydrochloride

Ca2+ channel blocker (L-type)

3395Lestaurtinib

JAK2, FLT3 and TrkA inhibitor

4382Letrozole

Potent, reversible non-steroidal aromatase inhibitor

4921Leukadherin 1

Allosteric activator of CD11b/CD18

2307Leukotriene B4

BLT1/BLT2 receptor agonist and potent chemotactic factor

1167Leupeptin hemisulfate

Inhibits trypsin-like/cysteine proteases

2873Leuprolide

GnRH receptor agonist

1378Levcromakalim

Kir6 (KATP) channel opener; active enantiomer of cromakalim (Cat. No. 1377)

2839Levetiracetam

Antiepileptic; binds SV2A

5529Levetiracetam - d6

Deuterated levetiracetam (Cat. No. 2839)

4833Levonorgestrel

Synthetic progesterone analog

4421LF 11

Antibiotic; neutralizes LPS

1300LFM-A13

Potent, selective BTK inhibitor

3831LG 100754

RXR:PPAR agonist

3508LG 101506

Selective RXR modulator

4896LH 846

Selective casein kinase 1δ inhibitor

2705Liarozole dihydrochloride

Blocks retinoic acid metabolism

3865Licarbazepine

Active metabolite of oxcarbazepine (Cat. No. 3864)

3057Lidocaine

Na+ channel blocker

4745LIMKi 3

Potent LIM kinase inhibitor; antitumor

3765Linezolid

Antibiotic; inhibits protein synthesis in gram-positive bacteria

1461Linomide

Immunomodulator with antiangiogenic properties

1999Linopirdine dihydrochloride

KV7 (KCNQ) channel blocker

5552Liothyronine sodium

Thyroid hormone (T3) analog; also promotes adipogenic differentiation of MSCs

3819Liquiritigenin

Selective ERβ agonist

4052Lisuride maleate

DA receptor agonist; antiparkinson's agent.

4740Lithium carbonate

Mood stabilizer; inhibits Na+/K+ ATPase pump activity

1916Litorin

Amphibian bombesin-like peptide

5213LL 37

Antimicrobial peptide derivative of human cathelicidin

5365LLY 507

Potent SMYD2 inhibitor

5794LM 10

Selective tryptophan 2,3-dioxygenase (TDO) inhibitor

4607LM 22A4

Potent TrkB agonist

5046LM11A 31 dihydrochloride

Nonpeptide p75NTR ligand; neuroprotective

4830LMK 235

Selective HDAC4/HDAC5 inhibitor

1077(-)-Lobeline hydrochloride

Nicotinic partial agonist

5606LOC14

High affinity protein disulfide isomerase (PDI) modulator

2690Locustatachykinin I

Insect tachykinin-related peptide (TRP)

2314LOE 908 hydrochloride

Broad spectrum cation channel blocker; neuroprotective

2545Lofepramine

5-HT and noradrenalin re-uptake inhibitor (SNRI)

4359Lomeguatrib

MGMT inhibitor

1646Lonidamine

Mitochondrial hexokinase inhibitor

0840Loperamide hydrochloride

Peripherally acting μ agonist; Ca2+ channel blocker

1944Loratidine

Peripheral H1 antagonist; antiallergic agent

3087Lorazepam

Acts at the benzodiazepine modulatory site

1295Loreclezole hydrochloride

Subtype-selective GABAA receptor modulator

3798Losartan potassium

Selective, non-peptide AT1 antagonist

1530Lovastatin

Potent HMG-CoA reductase inhibitor

2925LP 12 hydrochloride

5-HT7 agonist

4704LP 20 hydrochloride

Selective 5-HT7 ligand

2534LP 44

High affinity 5-HT7 agonist

4084LPYFD-NH2

Binds Aβ; protects from aggregation induced toxicity

3394LRGILS-NH2

Control peptide for SLIGRL-NH2 (Cat. No. 1468)

4273LRRK2-IN-1

Potent and selective LRRK2 inhibitor

5275LSN 2463359

Potent and selective positive allosteric modulator at mGlu5

4783Lu AA 47070

Prodrug of a potent and selective adenosine A2A receptor antagonist

3562LU AA33810

Potent NPY Y5 receptor antagonist

5427D-Luciferin sodium salt

Firefly luciferase substrate

4603LUF 5834

Potent adenosine A2A and A2B receptor partial agonist

4881LUF 6283

HCA2 (GPR109A) partial agonist

2874Luteolin

Anti-inflammatory, antioxidant and free radical scavenger

0877Luzindole

Competitive melatonin MT1/MT2 antagonist

4141LY 2087101

Potentiator of α7 nAChRs

1523LY 215840

5-HT2/5-HT7 antagonist

2452LY 2183240

Novel, potent anandamide uptake inhibitor; inhibits FAAH

1018LY 225910

Potent CCK2 antagonist

1286LY 231617

Antioxidant; neuroprotective in vitro and in vivo

1521LY 233053

Competitive NMDA receptor antagonist

1019LY 235959

Competitive NMDA antagonist

3397LY 2365109 hydrochloride

Potent and selective GlyT1 inhibitor

4969LY 2389575 hydrochloride

Selective negative allosteric modulator of mGlu3

2208LY 255283

Selective, competitive BLT2 receptor antagonist

4081LY 266097 hydrochloride

Selective 5-HT2B receptor antagonist

3077LY 272015 hydrochloride

High affinity 5-HT2B antagonist; orally active

1524LY 288513

Selective CCK2 antagonist

1130LY 294002 hydrochloride

Prototypical PI 3-kinase inhibitor; also inhibits other kinases

2418LY 303511

Negative control of LY 294002 (Cat. No. 1130)

3078LY 310762 hydrochloride

5-HT1D-preferring antagonist

3627LY 311727

Selective secreted phospholipase A2 (sPLA2) inhibitor

5313LY 315920

Selective secreted phospholipase A2 (sPLA2) inhibitor

2387LY 320135

Selective CB1 receptor antagonist/inverse agonist

4738LY 333531 hydrochloride

Protein kinase C inhibitor; selective for β isozymes

3079LY 334370 hydrochloride

Selective 5-HT1F agonist

1209LY 341495

Highly potent, selective group II antagonist

4062LY 341495 disodium salt

Disodium salt of LY 341495 (Cat. No. 1209)

2451LY 344864 hydrochloride

Potent, selective 5-HT1F agonist

3246LY 354740

Potent and highly selective group II mGlu agonist

2718LY 364947

Selective inhibitor of TGF-βRI

1237LY 367385

Selective mGlu1a antagonist

2453LY 379268

Highly selective group II mGlu agonist

5064LY 379268 disodium salt

Sodium salt of LY 379268 (Cat. No. 2453); selective group II mGlu receptor agonist

3350LY 393558

Dual 5-HT1B/1D antagonist and 5-HT re-uptake inhibitor

3272(±)-LY 395756

Mixed mGlu2 agonist/ mGlu3 antagonist

5297LY 404187

Selective AMPA receptor positive allosteric modulator

2390LY 456236 hydrochloride

Selective mGlu1 antagonist

3283LY 487379 hydrochloride

Positive allosteric modulator selective for mGlu2

4060LY 78335

Phenylethanolamine-N-methyltransferase inhibitor

2265Lyn peptide inhibitor

Inhibits Lyn-dependent activities of IL-5 receptor; cell-permeable

3611Lys-γ3-MSH

Pro-opiomelanocortin (POMC) derived peptide

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