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Displaying products alphabetically by name (G)

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Cat.No.
Product Name / Activity
5446G 28UCM

FASN inhibitor

3577G-1

Potent and selective GPER agonist

5944G10

Activator of STING-dependent signaling

3678G-15

High affinity and selective GPER antagonist

4759G-36

Selective GPER antagonist

4131G418 disulfate salt

Aminoglycoside antibiotic; used in cell culture

0344GABA

Endogenous agonist

0806Gabapentin

Anticonvulsant. Increases brain GABA

1798Gabexate mesylate

Serine protease inhibitor; inhibits thrombin, trypsin, kallikrein and plasmin

4741Gadolinium chloride

Stretch-activated calcium channel blocker; calcium-sensing receptor agonist

2696Galanin (1-29) (rat, mouse)

Non-selective galanin receptor agonist

3008Galanin (porcine)

Galanin receptor agonist

1450Galanin (1-15) (porcine, rat)

Galanin receptor agonist peptide

1179Galanin (1-30) (human)

Endogenous galanin receptor agonist

1451Galanin (2-29) (rat)

Selective GAL2 peptide agonist

0686Galanthamine hydrobromide

Cholinesterase inhibitor

3090Gallein

Inhibitor of βγ signaling

4795Galloflavin

Lactate dehydrogenase inhibitor; impairs aerobic glycolysis

2085Galnon

Non-selective galanin receptor agonist

3590Gambogic acid

Apoptosis inducer. Activates caspases and inhibits Bcl-2 family proteins

2531Ganaxolone

Potent, positive allosteric modulator of GABAA receptors

3889GANT 58

GLI1 antagonist; inhibits Hedgehog (Hh) signaling

3191GANT 61

GLI antagonist; inhibits Hedgehog (Hh) signaling

1950Gap 26

Gap junction blocker; inhibits smooth muscle contraction and IP3-mediated ATP release

1476Gap 27

Selective gap junction blocker

5353Gap19

Cx43 hemichannel blocker

4827Garcinol

PCAF/p300 inhibitor; anticancer

3006Gastrin I (human)

Selective CCK2 agonist

3849Gatifloxacin

Antibiotic; inhibits bacterial type II topoisomerase

4911GaTx2

High affinity, selective ClC-2 blocker; inhibits slow-gating

2348Gavestinel

Potent and selective glycine site antagonist; orally available and active in vivo

0513GBR 12783 dihydrochloride

Potent, selective dopamine uptake inhibitor

0421GBR 12909 dihydrochloride

Selective DA uptake inhibitor. Also σ ligand

0514GBR 12935 dihydrochloride

Selective dopamine uptake inhibitor

0420GBR 13069 dihydrochloride

Potent dopamine uptake inhibitor

4554GC 1

High affinity thyroid receptor α (TRα) and TRβ agonist; thyromimetic

4453GDC 0879

Potent B-Raf inhibitor

3387Gedunin

Hsp90 inhibitor; exhibits anticancer and antimalarial activity

1368Geldanamycin

Selective Hsp90 inhibitor

3259Gemcitabine hydrochloride

DNA synthesis inhibitor

1110Genistein

EGFR kinase inhibitor. Also estrogen and PPARγ ligand

0741GF 109203X

Protein kinase C inhibitor

4452GGsTop

Inhibitor of γ-glutamyl transpeptidase (GGT)

2430GGTI 298

Geranylgeranyltransferase I (GGTase I) inhibitor

1463Ghrelin (human)

Endogenous ghrelin receptor agonist

1465Ghrelin (rat)

Endogenous ghrelin receptor agonist

2951[Des-octanoyl]-Ghrelin (rat)

Major circulating form of ghrelin; devoid of activity at GHS receptor

1346des-Gln14-Ghrelin (rat)

Endogenous ghrelin receptor ligand

2260[Des-octanoyl]-Ghrelin (human)

Major circulating form of ghrelin; devoid of activity at ghrelin receptor but is active in vivo

1922[D-Lys3]-GHRP-6

Ghrelin receptor antagonist

3995GI 254023X

Selective ADAM10 metalloprotease inhibitor

1657Ginkgolide B

PAF receptor antagonist

2257GIP (1-39)

Highly potent insulinotropic peptide

2084GIP (human)

Potent insulinotropic gut hormone

5838[Pro3]-GIP (Mouse)

GIP receptor antagonist

5837[Pro3]-GIP (Rat)

High affinity rat GIP receptor partial agonist

4165Gisadenafil besylate

Potent PDE5 inhibitor; orally bioavailable

3270GIT 27

Immunomodulator; reduces production of pro-inflammatory cytokines

5133GKA 50

Glucokinase activator

0911Glibenclamide

Kir6 (KATP) channel blocker

2396Glimepiride

Kir6 (KATP) channel blocker

2637Gliotoxin

Inhibitor of 20S proteasome; immunosuppressant

5374GLP-1 (7-37)

Endogenous bioactive GLP-1 receptor ligand

3266GLP-1 (9-36) amide

Metabolite of GLP-1-(7-36) (Cat. No. 2082)

2258GLP-2 (human)

Endogenous hormone; displays intestinotrophic activity

2259GLP-2 (rat)

Endogenous hormone; displays intestinotrophic activity

5621GLPG 0974

Potent FFA2 antagonist

2216des-His1-[Glu9]-Glucagon (1-29) amide

Glucagon receptor antagonist

1851Glucagon-like peptide 1 (1-37) (human, rat)

Endogenous pancreatic peptide

2082Glucagon-like peptide 1 (7-36) amide (human, rat)

Potent insulinotropic peptide

0217D-Glutamic acid

Endogenous, non-selective agonist. Less active enantiomer

0218L-Glutamic acid

Endogenous, non-selective agonist

5219L-Glutathione Reduced

Endogenous antioxidant

5220Glycerol

Widely used in sample buffer preparation

0219Glycine

Endogenous potentiator, co-transmitter

5485GlyH 101

Reversible, voltage-dependent CFTR chloride channel blocker

3406GLYX 13

NMDA receptor partial agonist; acts at the glycine site

2983GM 6001

Broad spectrum MMP inhibitor

1883cGMP Dependent Kinase Inhibitor Peptide

Inhibitor of protein kinases G and A

5028GMQ hydrochloride

Selective ASIC3 opener

5655GN 44028

Potent HIF-1α inhibitor

4399GNF 2

Selective allosteric inhibitor of Bcr-Abl tyrosine kinase activity

4908GNF 5

Selective allosteric inhibitor of Bcr-Abl; analog of GNF 2 (Cat. No. 4399)

4559GNF 5837

Potent Trk inhibitor; inhibits TrkA, TrkB and TrkC

5607GNF 7

Ras signaling inhibitor; inhibits Ack1 and GCK

1282GNTI dihydrochloride

Potent, selective κ antagonist

29626'-GNTI dihydrochloride

Selective κ/δ opioid heterodimer receptor agonist

2253Go 6976

Potent protein kinase C inhibitor; selective for α and β isozymes

2285Go 6983

Broad spectrum PKC inhibitor

3584Golgicide A

Potent, specific and reversible inhibitor of GBF1 ArfGEF

3592Goserelin acetate

GnRH receptor agonist

1964Gossypol

Proapoptotic; downregulates Bcl-2 and Bcl-XL

2764GP 1a

Highly selective CB2 agonist

2678GP 2a

Selective CB2 agonist

4478GPBAR-A

GPBA receptor (TGR5) agonist

3967GPi 688

Allosteric glycogen phosphorylase inhibitor

4835GPP 78 hydrochloride

NAMPT inhibitor; also induces autophagy

1931G-Protein antagonist peptide

Inhibits G protein activation by GPCRs

1109GR 103691

Highly selective D3 antagonist

1322GR 113808

Potent, selective 5-HT4 antagonist

1658GR 125487 sulfamate

Potent, selective 5-HT4 antagonist; active in vivo

5453GR 125487 - d3 sulfamate

Deuterated GR 125487 (Cat. No. 1658)

1477GR 127935 hydrochloride

Potent, selective 5-HT1B/1D antagonist

0896GR 135531

High affinity melatonin MT3 ligand

1263GR 144053 trihydrochloride

Glycoprotein IIb/IIIa (integrin αIIbβ3) receptor antagonist. Antithrombotic

1274GR 159897

Non-peptide, potent NK2 antagonist

1486GR 231118

Potent NPY Y1 antagonist/NPY Y4 agonist. Binds to NPFF receptors

0864GR 46611

5-HT1D agonist

1054GR 55562 dihydrochloride

5-HT1B antagonist

1668GR 64349

Potent, selective NK2 agonist

1669GR 73632

Potent, selective NK1 agonist

1957GR 79236

A1 agonist

1670GR 82334

Tachykinin NK1 receptor antagonist

1483GR 89696 fumarate

Subtype-selective κ agonist

1667GR 94800

Potent, selective NK2 antagonist

2903Granisetron hydrochloride

5-HT3 antagonist

1172[Ac-Tyr1,D-Phe2]GRF 1-29, amide (human)

VIP receptor antagonist

4779GRI 977143

Selective LPA2 receptor non-lipid agonist

4581Grifolic acid

Selective partial FFA4 (GPR120) agonist

3594GRK2i

GRK2 inhibitory polypeptide. Gβγ antagonist

1826Group I mGlu Receptor Tocriset™

Selection of 5 group I mGlu receptor ligands (Cat. Nos. 0805, 0188, 1237, 1212 and 0337)

1827Group II mGlu Receptor Tocriset™

Selection of 5 group II mGlu receptor ligands (Cat. Nos. 1208, 0975, 1209, 0971 and 0337)

1828Group III mGlu Receptor Tocriset™

Selection of 5 group III mGlu receptor ligands (Cat. Nos. 0103, 1220, 0972, 0803 and 1209)

1789GRP (human)

Endogenous GRP receptor agonist

1788GRP (porcine)

Endogenous GRP receptor agonist

5636GS 143

β-TrCP1 ligase inhibitor

2001GS 39783

Positive modulator at GABAB receptors

4727GS 6201

Selective A2B antagonist

4918GSA 10

Smo receptor agonist

3433GSK 0660

Selective PPARδ antagonist

4026GSK 1059615

Potent PI 3-kinase inhibitor

5257GSK 137647

Potent and selective FFA4 (GPR120) agonist

5110GSK 1562590 hydrochloride

High affinity, selective urotensin II (UT) receptor antagonist

5111GSK 1838705

Potent IR and IGF1R inhibitor; also inhibits anaplastic lymphoma kinase (ALK)

5694GSK 2033

Potent LXR antagonist

5106GSK 2193874

Potent and selective TRPV4 antagonist; orally active

5303GSK 2194069

Potent human fatty acid synthase (hFASN) inhibitor

4143GSK 2334470

Highly potent, selective PDPK1 (PDK1) inhibitor

5107GSK 2606414

Potent and selective PERK inhibitor; orally bioavailable

3752GSK 264220A

Endothelial lipase and lipoprotein lipase inhibitor

4009GSK 269962

Potent and selective ROCK inhibitor

5635GSK 2801

Selective BAZ2A and BAZ2B inhibitor

5140GSK 2830371

Potent and selective allosteric inhibitor of Wip1 phosphatase

5189GSK 2837808A

Potent, selective LDHA inhibitor

3961GSK 3787

Potent and selective PPARδ antagonist

3663GSK 4112

Selective Rev-Erbα agonist

3726GSK 429286

Selective Rho-kinase (ROCK) inhibitor

3075GSK 4716

Selective ERRγ and ERRβ agonist

5385GSK 5959

Potent and selective BRPF1 inhibitor

3572GSK 650394

Serum- and glucocorticoid-regulated kinase (SGK) inhibitor

4144GSK 690693

Akt kinase inhibitor. Antitumor

3940GSK 789472 hydrochloride

D3 antagonist. Also D2 partial agonist

4116GSK 9027

Glucocorticoid receptor agonist

4593GSK J1

Potent JMJD3/UTX inhibitor

4688GSK J2

Inactive isomer of GSK J1 (Cat. No. 4593)

4594GSK J4

Histone KDM inhibitor; cell permeable

4689GSK J5

Inactive isomer of GSK J4 (Cat. No. 4594); cell permeable

5361GSK LSD 1 dihydrochloride

Potent and selective LSD1 inhibitor

4629GSK2578215A

Potent, selective LRRK2 inhibitor; brain penetrant

4912GsMTx4

TRPC1 and TRPC6 blocker; inhibits mechanosensitive ion channels

2419GT 2016

Selective H3 antagonist

2086GTP 14564

Class III receptor tyrosine kinase (RTK) inhibitor

4557GTS 21 dihydrochloride

Partial agonist at α7 nAChR

0885Guanabenz acetate

α2 agonist. Also I2 selective ligand

1030Guanfacine hydrochloride

α2A agonist

5676Guangxitoxin 1E

Potent Kv2.1 and Kv2.2 channel blocker

5221Guanidine Hydrochloride

Protein denaturant

1898Guanylin (human)

Endogenous activator of intestinal guanylyl cyclase

4742Gue 1654

Selective inhibitor of OXE-R Gβγ signaling

2013Guggulsterone

Broad spectrum steroid receptor ligand. Antagonizes FXR and displays hypolipidemic activity

3570Z-Guggulsterone

Broad spectrum steroid receptor ligand. More active isomer of guggulsterone (Cat. No. 2013)

0234Guvacine hydrochloride

Specific GABA uptake inhibitor

2229GW 0742

Highly selective, potent PPARδ agonist

1664GW 1929 hydrochloride

Selective PPARγ agonist. Orally active

5673GW 2580

Selective cFMS kinase inhibitor; orally bioavailable

2474GW 3965 hydrochloride

Orally active liver X receptor (LXR) agonist

2374GW 405833

Selective, high affinity CB2 receptor partial agonist

2473GW 4064

Selective farnesoid X receptor (FXR) agonist

4669GW 438014A

NPY Y5 receptor antagonist

2238GW 441756

Potent, selective TrkA inhibitor

5674GW 501516

Potent and selective PPARδ agonist

1381GW 5074

Potent, selective c-Raf1 kinase inhibitor

4311GW 542573X

Selective activator of KCa2.1 channels

2239GW 583340 dihydrochloride

Potent dual EGFR/ErbB2 inhibitor; orally active

4668GW 627368

Selective EP4 receptor competitive antagonist

4618GW 6471

PPARα antagonist

1677GW 7647

Highly selective, potent PPARα agonist. Orally active

3264GW 788388

Potent and selective inhibitor of TGF-βRI

3385GW 791343 hydrochloride

P2X7 allosteric modulator

4242GW 803430

MCH1 antagonist

2977GW 843682X

Selective inhibitor of PLK1 and PLK3

2649GW 9508

Potent and selective FFA1 (GPR40) agonist

1508GW 9662

Selective PPARγ antagonist

3099GYKI 47261 dihydrochloride

Non-competitive AMPA antagonist

1454GYKI 52466 dihydrochloride

Selective non-competitive AMPA antagonist

2555GYKI 53655 hydrochloride

Non-competitive AMPA receptor antagonist

3658GYY 4137 morpholine salt

Slow-releasing H2S donor

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