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Displaying products alphabetically by name (E)

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Cat.No.
Product Name / Activity
5208E 64

Potent and irreversible cysteine protease inhibitor

4545E 64d

Cathepsin inhibitor; interferes with autolysosomal digestion

1808E-4031 dihydrochloride

KV11.1 (hERG) channel blocker; inhibits rapid delayed rectifier K+ current (IKr)

1009E4CPG

Group I/group II mGlu antagonist

4876Eact

Activator of Ca2+-activated Cl- channel transmembrane protein 16A (TMEM16A)

3993EB 1089

Vitamin D receptor (VDR) agonist

4140EB 47

Potent PARP-1 inhibitor

10411-EBIO

Activator of epithelial KCa channels

0518EBPC

Aldose reductase inhibitor

5245Ebselen

Glutathione peroxidase mimic; peroxynitrite scavenger

4701EC 144

High affinity, potent and selective Hsp90 inhibitor

5849EC 19

Synthetic retinoid; induces differentiation of stem cells

4011EC 23

Synthetic retinoid; induces differentiation of stem cells

5520Echinomycin

Highly potent and selective HIF-1α inhibitor

3202Echistatin, α1 isoform

αVβ3 and glycoprotein IIb/IIIa (integrin αIIbβ3) inhibitor

4784Edaglitazone

Potent and selective PPARγ agonist; antidiabetic

0786Edaravone

Anti-ischemic and antioxidant

3022Edelfosine

Selective PI-PLC inhibitor, also PAF receptor agonist

2811EDTA

Chelating agent

3922Eeyarestatin I

Potent inhibitor of ER-associated protein degradation and translocation

0792Efaroxan hydrochloride

α2 antagonist and I1, I3 ligand

3733Efonidipine hydrochloride monoethanolate

Ca2+ channel blocker (L- and T-type)

4931EG 00229

Neuropilin 1 (NRP1) receptor antagonist; inhibits VEGFA binding to NRP1

4524EGCG

Inhibits formation of amyloid fibrils

5695Eggmanone

Potent and selective PDE4 inhibitor; suppresses hedgehog signaling

0971EGLU

Highly selective group II mGlu antagonist

2807EGTA

Calcium chelating agent

1261EHNA hydrochloride

Adenosine deaminase inhibitor

3872EHT 1864

Potent inhibitor of Rac family GTPases

5979Eicosapentaenoic Acid

Endogenous polyunsaturated fatty acid; stimulates ERK1/2 phosphorylation

3378EIPA

Inhibits TRPP3-mediated currents; also inhibits the Na+/H+ exchanger (NHE)

0873EIT hydrobromide

Selective iNOS inhibitor, acts arginine binding site

4646Elacridar hydrochloride

P-gp inhibitor

1914Eledoisin

Potent tachykinin receptor ligand

1920Eledoisin-Related Peptide

Tachykinin receptor ligand

3862Eletriptan hydrobromide

Orally active, selective 5-HT1B/1D agonist

5316Elinogrel

P2Y12 antagonist

2195Eliprodil

Non-competitive NR2B-selective NMDA antagonist

3058Ellagic acid

Selective inhibitor of CK2. Also inhibits glutathione S-transferase

3357Ellipticine

Antitumor and intercalating agent; inhibits DNA topoisomerase II

1860Eltoprazine hydrochloride

5-HT1 receptor agonist/partial agonist

2156Embelin

Inhibitor of X-linked inhibitor of apoptosis (XIAP); cell-permeable and antitumor

4470EMD 281014 hydrochloride

Selective 5-HT2A antagonist

2382EMD 386088 hydrochloride

Potent 5-HT6 agonist

1849EMD 66684

Potent, selective non-peptide AT1 antagonist

4209EMDT oxalate

Selective 5-HT6 agonist

5646EML 425

Reversible and non-competitive p300/CBP inhibitor

3811Emodin

Naturally occurring anthraquinone; displays anti-inflammatory, antitumor and neuroprotective activity

4558EMPA

Highly potent and selective OX2 antagonist; brain penetrant

3576(±)-5'-Chloro-5'-deoxy-ENBA

Highly selective A1 agonist

1055Endomorphin-1

Potent and selective μ agonist

1056Endomorphin-2

Potent and selective μ agonist

1160Endothelin 1 (human, porcine)

Potent vasoconstrictor peptide

1164Endothelin 2 (human)

ETA/ETB agonist

1162Endothelin 3 (human, rat)

Potent vasoconstrictor

1197[Ala1,3,11,15]-Endothelin

Selective ETB agonist

3705Endoxifen

Potent antiestrogen; ERα ligand

1889[Leu5]-Enkephalin

Endogenous opioid agonist peptide

1693Enoximone

PDE3 inhibitor

4720Entacapone

Potent COMT inhibitor; blocks α-synuclein aggregation

5994Enzastaurin

Potent PKCβ inhibitor

2908EO 1428

Selective inhibitor of p38α and p38β2

0684(±)-Epibatidine

High affinity nicotinic agonist

3260Epirubicin hydrochloride

Inhibits DNA synthesis and function. Inhibits DNA topoisomerase II

2397Eplerenone

Selective mineralocorticoid receptor antagonist

4958Eplivanserin hemifumarate

Potent and selective 5-HT2A antagonist

2989Epoprostenol

Endogenous IP receptor agonist

3502Epothilone B

Microtubule stabilization agent; promotes tubulin polymerization

4518EPPTB

Trace amine 1 (TA1) receptor antagonist/inverse agonist

4696Eprosartan mesylate

Potent and selective AT1 receptor antagonist

4725Eptifibatide

Glycoprotein IIb/IIIa inhibitor; inhibits platelet aggregation

5567EPZ 004777

Highly potent DOT1L inhibitor

2471ER 27319 maleate

Selective Syk kinase inhibitor

3823ER 50891

Selective RARα antagonist

5449Erastin

Mitochondria VDAC modulator; also Ferroptosis activator

4276ERB 041

Potent ERβ agonist

4146Ercalcidiol

Metabolite of vitamin D2

3970Ercalcitriol

Active metabolite of vitamin D2

5393ERK5-IN-1

Potent and selective ERK5 inhibitor

4796Escitalopram oxalate

Selective serotonin reuptake inhibitor (SSRI)

4773ESI 09

EPAC inhibitor

2823α-Estradiol

Endogenous estrogen receptor agonist

2824β-Estradiol

Endogenous ER agonist

3588Estropipate

Estrogen receptor agonist and OATP1B1 inhibitor

0438Etazolate hydrochloride

PDE4 inhibitor

4987Ethacrynic acid - d5

Deuterated ethacrynic acid

57124-ethynyl-N-ethyl-1,8-naphthalimide

Click-activated fluorescent probe

1847Eticlopride hydrochloride

Selective D2/D3 antagonist

3113Etifoxine hydrochloride

Ligand of the translocator protein (TSPO); also GABAA receptor potentiator

3871Etodolac

Selective cyclooxygenase-2 (COX-2) inhibitor; NSAID

1471Etomidate

GABA mimetic and GABA modulatory agent

4539(R)-(+)-Etomoxir sodium salt

Carnitine palmitoyltransferase I (CPT1) inhibitor

1226Etoposide

Topoisomerase II inhibitor

4702ETP 45658

Potent PI 3-kinase inhibitor; also inhibits DNA-PK and mTOR

5183ETP 45835 dihydrochloride

Mnk1 and Mnk2 inhibitor

0845Evans Blue tetrasodium salt

Potent inhibitor of L-glutamate uptake into synaptic vesicles

2780EX 527

Selective SIRT1 inhibitor

1830Excitatory Amino Acid Transporter Inhibitor Tocriset™

Selection of 5 EAAT inhibitors (Cat. Nos. 0183, 0298, 1223, 0111 and 0903)

3759Exemestane

Steroidal aromatase (CYP19) inhibitor

2081Exendin-3 (9-39) amide

Potent GLP-1 receptor antagonist

1933Exendin-4

Potent GLP-1 receptor agonist

1850Exo1

Inhibits Golgi-ER traffic; blocks exocytosis

5728EXP 3174

Potent and selective AT1 receptor antagonist

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