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Displaying products alphabetically by name (D)

ABCDEFGHIJKLMNOPQRSTUVWXYZ
Cat.No.
Product Name / Activity
5504D-(+)-Glucose

Naturally occurring monosaccharide

2334D15

Endocytosis blocker

2902D 4476

Selective CK1 inhibitor. Also inhibits TGF-βRI

1437D609

Selective PC-PLC inhibitor

1643D-64131

Tubulin polymerization inhibitor. Antitumor in vivo

3790DADLE

Prototypical δ agonist

1417Daidzein

Arrests cell cycle in G1 phase

1171DAMGO

Selective μ agonist

4684Daminozide

Selective KDM2/7 inhibitor

1936Damnacanthal

Potent, selective p56lck inhibitor; also LIMK1/2 inhibitor

04824-DAMP

Muscarinic M3 antagonist

5122Dansyl-NECA

Potent and selective fluorescent adenosine A1 agonist

0507Dantrolene, sodium salt

Ca2+ release inhibitor

5748DAPI

Fluorescent DNA stain

1458DAPK Substrate Peptide

Death associated protein kinase substrate (synthetic)

4358Dapoxetine hydrochloride

Selective serotonin reuptake inhibitor

2634DAPT

γ-secretase inhibitor

2423DAPTA

Chemokine receptor 5 (CCR5) antagonist

3917Daptomycin

Antibiotic; inhibits protein, DNA and RNA synthesis in gram-positive bacteria

2096DAU 5884 hydrochloride

M3 receptor antagonist

1467Daunorubicin hydrochloride

RNA synthesis inhibitor

4417DBeQ

Selective and reversible p97 ATPase inhibitor

5095DBM 1285 dihydrochloride

p38 MAPK inhibitor; anti-inflammatory

4489DBZ

γ-secretase inhibitor; inhibits Notch pathway

5357DC 260126

FFA1 (GPR40) antagonist

2755DCA

Mitochondrial pyruvate dehydrogenase kinase (PDK) inhibitor

1952DCB

Allosteric modulator at mGlu5

1422DCEBIO

Activates Cl- conductance and hKCa3.1 channels

0975DCG IV

Very potent, selective group II mGlu agonist. Also NMDA agonist

21372,3-DCPE hydrochloride

Selectively induces cancer cell apoptosis

1395(R)-3,4-DCPG

AMPA antagonist/weak NMDA antagonist

1394(RS)-3,4-DCPG

Potent systemically active anticonvulsant. Racemate of (R)-3,4,-DCPG (Cat. No. 1395)

1302(S)-3,4-DCPG

Potent, selective mGlu8a agonist

1540DCPIB

Selective blocker of VSAC/ICl, swell. Inhibits glucose-stimulated insulin release

5077DDR1-IN-1 dihydrochloride

Selective DDR1 inhibitor

1485DEA

Endogenous CB1 agonist

44881-Deazaadenosine

Adenosine deaminase inhibitor

47033-Deazaneplanocin A hydrochloride

EZH2 histone methyltransferase inhibitor

255810-DEBC hydrochloride

Selective Akt/PKB inhibitor

0477(±)-Decanoylcarnitine chloride

Intermediate in lipid metabolism

3501Decanoyl-RVKR-CMK

Subtilisin/Kex2p-like proprotein convertase inhibitor

2624Decitabine

DNA methyltransferase inhibitor

4722Decynium 22

PMAT inhibitor

5764Deferoxamine mesylate

Iron chelator; also hypoxia mimetic

1770Deguelin

Anticancer and antiviral agent; chemopreventive and pro-apoptotic

5734L-Dehydroascorbic acid

GLUT1 substrate; oxidized form of L-Ascorbic acid

5774DEL 22379

ERK dimerization inhibitor

4149Delavirdine mesylate

Non-nucleoside reverse transcriptase inhibitor

5424Deltarasin

High affinity PDEδ-KRAS interaction inhibitor

4591Deltorphin I

Potent δ agonist

1180[D-Ala2]-Deltorphin II

Selective δ agonist peptide

1819Demethylasterriquinone B1

Selective insulin RTK activator

45152-Deoxy-D-glucose

Non-metabolizable glucose analog; hexokinase substrate

12591-Deoxymannojirimycin hydrochloride

α-Mannosidase I inhibitor

3976Deoxynivalenol

Mycotoxin; potent protein synthesis inhibitor

12581-Deoxynojirimycin

Glucosidase I and II inhibitor

1095(R)-(-)-Deprenyl hydrochloride

MAO-B inhibitor

3328Desformylflustrabromine hydrochloride

Positive allosteric modulator of α4β2; also muscle-type nAChR inhibitor

3067Desipramine hydrochloride

Selective inhibitor of noradrenalin transporters

5958Desloratadine

High affinity H1 antagonist; anti-inflammatory.

1007N-Desmethylclozapine

5-HT2C antagonist

3396Desmopressin

Synthetic vasopressin analog; V1B and V2 agonist

2304Devazepide

Selective, orally active CCK1 receptor antagonist

2166Z-DEVD-FMK

Cell-permeable, irreversible caspase-3 inhibitor

1126Dexamethasone

Anti-inflammatory glucocorticoid

2695Dexfenfluramine hydrochloride

5-HT re-uptake inhibitor. Also stimulates 5-HT release

2749Dexmedetomidine hydrochloride

Potent, highly selective α2 agonist. Active isomer of medetomidine (Cat. No. 5160)

3857Dexrazoxane hydrochloride

Topoisomerase II inhibitor

3071Dextromethorphan hydrobromide

NMDA receptor antagonist

1625DFB

Allosteric potentiator at mGlu5

5609DFHBI

Mimic of GFP fluorophore for imaging RNA in living cells

5610DFHBI 1T

Mimic of GFP fluorophore for imaging RNA in living cells

2761DFMO

Ornithine decarboxylase inhibitor

5566DG 172 dihydrochloride

Potent PPARβ/δ inverse agonist; promotes BMC differentiation

0112γDGG

Broad spectrum glutamate receptor antagonist

1218DH 97

MT2 receptor antagonist

45993,5-DHBA

Selective HCA1 agonist

0839DHBP dibromide

Ca2+ release inhibitor

0342(RS)-3,5-DHPG

Selective group I mGlu agonist

0805(S)-3,5-DHPG

Selective group I mGlu agonist. Active enantiomer of 3,5-DHPG (Cat. No. 0342)

04762,4-Diamino-6-hydroxypyrimidine

Inhibits tetrahydrobiopterin synthesis and thus NOS activity

5557Dianicline

Selective α4β2 nAChR partial agonist

2805Diazepam

Acts at the benzodiazepine modulatory site

0964Diazoxide

Blocks desensitization of AMPA receptors

3416Tris DBA

N-myristoyltransferase-1 inhibitor; antiproliferative

1141Dibutyryl-cAMP, sodium salt

Cell-permeable cAMP analog

02865,7-Dichlorokynurenic acid

Potent NMDA antagonist, acts glycine site

36985,7-Dichlorokynurenic acid sodium salt

Sodium salt of 5,7-Dichlorokynurenic acid (Cat. No. 0286). Potent NMDA antagonist, acts at glycine site

4454Diclofenac sodium salt

Cyclooxygenase inhibitor; NSAID

5702DiD perchlorate

Lipophilic fluorescent reagent; shown to stain HSCs

50341,9-Dideoxyforskolin

Inactive analog of forskolin (Cat. No. 1099)

4523DIDS

Chloride channel blocker; TRPV1 modulator; RAD51 recombinase inhibitor

0468N1,N11-Diethylnorspermine tetrahydrochloride

Spermine and spermidine acetyltransferase potentiator

0500N1,N12-Diethylspermine tetrahydrochloride

Polyamine synthase inhibitor

2145Difopein

High affinity inhibitor of 14.3.3 proteins; induces apoptosis

4583Digoxin

Na+/K+ ATPase inhibitor

0884Dihydrexidine hydrochloride

Selective D1-like agonist

2349Dihydro-β-erythroidine hydrobromide

Antagonist for neuronal α4-containing nicotinic receptors

0474Dihydroergocristine mesylate

Partial α agonist. Non-selective

0475Dihydroergotamine mesylate

Partial α agonist. Non-selective

0505Dihydroergotoxine mesylate

Binds to GABAA receptor Cl- channel; allosteric modulator of benzodiazepine site

0111Dihydrokainic acid

EAAT2 (GLT-1)-selective non-transportable inhibitor of L-glutamate and L-aspartate uptake

0749Dihydrosphingosine

Protein kinase C inhibitor

38267,8-Dihydroxyflavone

TrkB agonist

02622,4-Dihydroxyphenylacetyl-L-asparagine

Component of Joro spider toxin

0481Dilazep dihydrochloride

Adenosine uptake inhibitor

0685Diltiazem hydrochloride

Ca2+ channel blocker (L-type)

4502DIM

Activates Chk2; induces G2/M cell cycle arrest

0506Dimaprit dihydrochloride

Standard H2 selective agonist

3201Dimebon dihydrochloride

Neuroprotectant; protects against β-amyloid neurotoxicity

1425(S)-(+)-Dimethindene maleate

M2-selective antagonist

5261Dimethylenastron

Inhibitor of mitotic motor kinesin Eg5

402716,16-Dimethyl Prostaglandin E2

Synthetic prostaglandin E2 (Cat. No. 2296) derivative; regulates HSC development

4640N,N-Dimethylsphingosine

Sphingosine kinase inhibitor

4628DiMNF

Selective aryl hydrocarbon receptor modulator (SAhRM)

0484Dioctanoylglycol

Diacylglycerol kinase inhibitor

3072Diphenhydramine hydrochloride

H1 receptor antagonist

0504Diphenyleneiodonium chloride

GPR3 agonist; also inhibits NOS and NADPH oxidases

0360(±)-1-(1,2-Diphenylethyl)piperidine maleate

NMDA antagonist, acts ion channel site

0794DIPPA hydrochloride

Selective irreversible κ antagonist

2965Diprenorphine

Non-selective opioid antagonist

04861,3-Dipropyl-8-phenylxanthine

A1 selective antagonist

0691Dipyridamole

Adenosine transport inhibitor

3807Disulfiram

Reversibly stimulates SERCA Ca2+-ATPase; displays a range of other activities

3154DL-Dithiothreitol

Maintains SH groups in the reduced state

4378DLPC

LRH-1 agonist; regulates bile acid metabolism

2241DMAB-anabaseine dihydrochloride

Partial agonist at α7 nAChR; also α4β2 antagonist

261017-DMAG hydrochloride

Water-soluble Hsp90 inhibitor

3083DMCM hydrochloride

Benzodiazepine inverse agonist

1953DMeOB

Negative allosteric modulator at mGlu5

4512DMF

Nrf2 pathway activator; neuroprotective

4126DMH-1

Selective ALK2 inhibitor

5580DMH2

Type I BMP receptor inhibitor

4471DMH4

Selective VEGFR-2 inhibitor

1481(-)-5'-DMH-CBD

Metabolically stable anandamide transport inhibitor

2088DMNB

DNA-PK inhibitor

5157DMNPE-caged ATP diammonium salt

Caged ATP

4408DMOG

Prolyl hydroxylase inhibitor

2330DMP 543

K+ channel blocker and potent ACh release enhancer

3415DMPO

Nitric oxide spin trap; measure oxygen-centered free radicals

1222DMPQ dihydrochloride

Potent, selective inhibitor of PDGFRβ

3176DMSO, sterile filtered

Solvent

3428DMT

Endogenous σ1 ligand. Also 5-HT2A agonist

5601DMXAA

mSTING agonist; induces antitumor immunological responses

0189DNQX

Selective non-NMDA antagonist

2312DNQX disodium salt

Selective non-NMDA antagonist. Water-soluble salt of DNQX (Cat. No. 0189)

2863DOB hydrochloride

Selective 5-HT2 agonist

0515Dobutamine hydrochloride

α1, β1 and β2 agonist

4056Docetaxel

Microtubule stabilizer

3687Docosahexaenoic acid

RXR agonist

3757Dofetilide

KV11.1 (hERG) channel blocker; inhibits rapid delayed rectifier K+ current (IKr)

2643DOI hydrochloride

Mixed 5-HT2A/2C agonist

5629Dolasetron mesylate

Potent and selective 5-HT3 antagonist

3375Dolastatin 10 trifluoroacetate

Tubulin polymerization inhibitor

0269Domoic acid

Potent, selective kainate agonist

2536Domperidone

Peripheral D2-like antagonist

5544Donepezil - d5 hydrochloride

Deuterated donepezil (Cat. No. 4385)

4385Donepezil hydrochloride

Potent AChE inhibitor

3665Donitriptan hydrochloride

5-HT1B/1D agonist

3548Dopamine hydrochloride

Endogenous agonist at dopamine D1-5 receptors

3093Dorsomorphin dihydrochloride

Potent AMPK inhibitor

2964Doxazosin mesylate

α1 antagonist

0508Doxepin hydrochloride

Highly potent H1 antagonist. Also binds to H4 receptor

3206Doxercalciferol

Vitamin D2 analog, VDR agonist

2252Doxorubicin hydrochloride

Antitumor antibiotic agent. Inhibits DNA topoisomerase II

4090Doxycycline hyclate

Broad-spectrum MMP inhibitor; tetracycline derivative

5487DPC AJ1951

Potent parathyroid hormone (PTH) receptor agonist

0439DPCPX

A1 selective antagonist

1431DPDPE

Selective δ agonist

1494DPN

Highly potent ERβ agonist

4494(R)-DPN

Enantiomer of DPN (Cat. No. 1494)

2991DPNI-caged-GABA

Nitroindoline-caged GABA

2533DPO-1

Blocker of KV1.5 channel and IKur current

0743DPPE fumarate

Inhibitor of histamine binding at the intracellular binding site

2783DPPI 1c hydrochloride

Dipeptidyl peptidase IV (DPP-IV) inhibitor

2168Z-DQMD-FMK

Caspase-3 inhibitor

4491DQP 1105

Selective NR2C/NR2D receptor antagonist

2496DR 2313

PARP-1 and PARP-2 inhibitor

5005DR 4485 hydrochloride

High affinity and selective 5-HT7 antagonist; orally bioavailable

5548DREADD agonist 21

Potent hM3Dq DREADD agonist

3610(R)-DRF053 dihydrochloride

Dual CK1/cdk inhibitor

5858Droperidol

D2 receptor antagonist

3679DS2

Positive allosteric modulator of δ-containing GABAA receptors

2958DSP-4

Adrenergic neurotoxin

4809DSR 6434

Potent TLR7 agonist

0841DTG

High affinity ligand (σ1 = σ2)

3156Dulbecco's PBS

Buffered saline used in mammalian cell culture

4798(S)-Duloxetine hydrochloride

Potent 5-HT and NA reuptake inhibitor; also blocks dopamine reuptake

1430DuP 697

Cyclooxygenase-2 (COX-2) inhibitor

4480DV 7028 hydrochloride

Selective 5-HT2A antagonist; antithrombotic

5656DY 268

Potent FXR antagonist

2266DY131

Agonist selective for estrogen-related receptors ERRβ and ERRγ

1774Dynamin inhibitory peptide

Dynamin inhibitor

1775Dynamin inhibitory peptide, myristoylated

Cell-permeable dynamin inhibitor

1776Dynamin inhibitory peptide, myristoylated (control)

Control peptide version of dynamin inhibitory peptide, myristoylated (Cat. No. 1775)

2897Dynasore

Non-competitive dynamin inhibitor

4222Dynole 34-2

Dynamin I inhibitor

3195Dynorphin A

Endogenous κ agonist

3196Dynorphin B

Endogenous κ agonist

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