Tocris Bioscience

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Product Pages Catalogue Numbers 1201 - 1300

Cat. No. Product Name & Pharmacological Action
1201Phorbol 12-myristate 13-acetate
Protein kinase C activator
1202SB 203580
Selective inhibitor of p38 MAPK
1203MRS 2219
Potentiates P2X1-mediated responses
1205SR 57227 hydrochloride
Potent, selective 5-HT3 agonist
1206SC 19220
Selective EP1 receptor antagonist
1207BRL 15572 hydrochloride
Selective h5-HT1D antagonist
1208(2R,4R)-APDC
Highly selective group II agonist
1209LY 341495
Highly potent, selective group II antagonist
1210FR 139317
Highly potent, selective ETA antagonist
1211ZD 7155 hydrochloride
Selective non-peptide AT1 antagonist
1212MPEP hydrochloride
mGlu5 antagonist and positive allosteric modulator at mGlu4
1213PD 98059
Specific inhibitor of MEK
1214SIB 1893
mGlu5 antagonist and positive allosteric modulator at mGlu4
1215SIB 1757
Highly selective mGlu5 antagonist
1217MRS 1220
Highly potent, selective hA3 antagonist
1218DH 97
MT2 receptor antagonist
1219IDRA 21
Inhibits AMPA receptor desensitisation
1220(RS)-PPG
Potent, selective mGlu8 agonist
1221SB 224289 hydrochloride
Selective 5-HT1B antagonist
1222DMPQ dihydrochloride
Potent, selective inhibitor of β-type PDGFRTK
1223DL-TBOA
Potent, selective non-transportable inhibitor of EAATs
12242-APB
IP3 receptor antagonist. Also TRP channel modulator
1226Etoposide
Topoisomerase II inhibitor
1227Apigenin
Anticancer agent
1228Nocodazole
Microtubule inhibitor
1229Actinomycin D
Antineoplastic antibiotic
1230Methotrexate
Cytotoxic agent
1231Brefeldin A
Disrupts protein translocation to Golgi
1232Wortmannin
Potent, irreversible inhibitor of PI 3-kinase. Also inhibitor of PLK1
1233Cytochalasin D
Disrupts actin filament function
1234A23187, free acid
Calcium ionophore
1235Cyclopiazonic Acid
Inhibitor of SERCA ATPase
1236BHQ
Inhibitor of SERCA ATPase
1237LY 367385
Selective mGlu1a antagonist
1238CCMQ
Used to characterise NR2B-containing NMDA receptors
1239Ac-RYYRIK-NH2
High affinity ORL1 ligand
1240NF 023
Selective, competitive P2X antagonist
1241CGS 19755
Potent, competitive NMDA antagonist
1242SB 216641 hydrochloride
Selective h5-HT1B antagonist
1243(+)-PD 128907 hydrochloride

D3 agonist (D3 ³ D2 > D4)

1244KB-R7943 mesylate
Na+/Ca2+ exchange inhibitor (reverse mode)
1245CGP 35348
 Brain penetrant, selective GABAB antagonist
1246CGP 52432
Potent, selective GABAB antagonist
1247CGP 46381
Brain penetrant, selective GABAB antagonist
1248CGP 55845
Potent, selective GABAB antagonist
1249CY 208-243

Selective D1-like agonist

1250SDZ 220-581
Competitive NMDA antagonist, centrally active
1251SDZ 220-040
Potent, competitive NMDA antagonist
1253(S)-WAY 100135 dihydrochloride
Potent, selective 5-HT1A antagonist
1254Y-27632 dihydrochloride
Selective p160ROCK inhibitor
1255SDZ SER 082 fumarate
Selective 5-HT2B/2C antagonist
1256Vinblastine sulfate
Disrupts microtubules
1257Vincristine sulfate
Disrupts microtubules
12581-Deoxynojirimycin
Glucosidase I and II inhibitor
12591-Deoxymannojirimycin hydrochloride
α-Mannosidase I inhibitor
1260Ivermectin
Modulates glutamate/GABA-activated CI- channels
1261EHNA hydrochloride
Adenosine deaminase inhibitor
1262SR 95531 hydrobromide
Selective, competitive GABAA receptor antagonist
1263GR 144053 trihydrochloride
Fibrinogen (glycoprotein IIb/IIIa) receptor antagonist. Antithrombotic
1264SB 202190
Potent, selective inhibitor of p38 MAPK
1265D-CPP-ene
Potent, competitive NMDA antagonist
1266Nociceptin (1-7)
Bioactive metabolite of nociceptin
1267Pifithrin-α hydrobromide
p53 inhibitor. Also aryl hydrocarbon receptor agonist
1268U 73122
Phospholipase C inhibitor
1274GR 159897
Non-peptide, potent NK2 antagonist
1276AG 1478 hydrochloride
Highly potent EGFR-kinase inhibitor
1277KN-62
Non-competitive P2X7 antagonist
1278KN-93
CaM kinase II inhibitor. Also K+ channel blocker (KV)
1282GNTI dihydrochloride
Potent, selective κ antagonist
1283ARL 67156 trisodium salt
Ecto-ATPase inhibitor
1284Olomoucine
Cyclin-dependent kinase inhibitor
1285Staurosporine
Non-selective protein kinase inhibitor
1288KT 5720
Selective protein kinase A inhibitor
1289KT 5823
Selective protein kinase G inhibitor
1290Anisomycin
Protein synthesis inhibitor
1291Ochratoxin A
Stimulates SERCA-ATP-dependent Ca2+ pump activity
1292Rapamycin
Immunosuppressant
1295Loreclezole hydrochloride
Subtype-selective GABAA receptor modulator
1296CI 966 hydrochloride
Selective inhibitor of GAT-1
1297Abn-CBD

Neurobehaviourally inactive cannabinoid

12982-Arachidonylglycerol

Endogenous cannabinoid agonist

1300LFM-A13
Potent, selective BTK inhibitor
 
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