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Category: EnzymesarrowKinasesarrowProtein Kinase G
Cat.No. Product Name
3028 Rp-8-Br-PET-cGMPS
Price and Availability

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Rp-8-Br-PET-cGMPS

Other Information:

This product is sold in units of 560ug, equivalent to 1umol.
Chemical Name: 2-Bromo-3,4-dihydro-3-[3,5-O-[(R)-mercaptophosphinylide ne]-ß-D-ribofuranosyl]-6-phenyl-9H-Imidazo[1,2-a]purin- 9-one sodium salt

Biological Activity:

Competitive, reversible cGMP-dependent protein kinase (PKG) inhibitor.

Technical Data:

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M.Wt: 562.27
Formula: C18H14BrN5NaO6PS
Storage: Store at -20°C
Solubility: Soluble to 20 mM in Water and to 40 mM in DMSO
Purity: >99%
CAS No: [172806-20-1]

Resources:

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    • Certificate of Analysis / MSDS:

    Certificate of Analysis: View current batch
    Product/Material Safety Data Sheet: View current batch

    References:

    Wei et al (1996) Identification of competitive antagonists of the rod photoreceptor cGMP-gated cation channel: beta-phenyl-1,N2-etheno-substituted cGMP analogues as probes of the cGMP-binding site. Biochemistry 35 16815. Qi et al (2007) Protein kinase G regulates the basal tension and plays a major role in nitrovasodilator-induced relaxation of porcine coronary veins. Br.J.Pharmacol. 152 1060.
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    Keywords: Rp-8-Br-PET-cGMPS, Kinases, Protein Kinase G Inhibitor, Rp8-Br-PET-cGMPS, Tocris Bioscience
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