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Category:
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7TM Receptors Adrenergic ReceptorsBeta-3 Receptors
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Cat.No.
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Product Name
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2154 |
ZD 2079
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Price and Availability
Click here for full price details of
ZD 2079
Other Information:
Sold with
the permission of AstraZeneca UK Ltd
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Chemical Name:
4-[2-[[(2R)-2-Hydroxy-2-phenylethyl]amino]ethoxy]-benze
neacetic acid hydrochloride |
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Biological Activity:
β3-adrenoceptor agonist. Relaxes rat
mesenteric artery and isolated aorta in vitro. Inhibits ob gene expression and
circulating leptin levels in lean mice in vivo.
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
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References:
Trayhurn et al (1996) Rapid inhibition
of ob gene expression and circulating leptin levels in lean mice by the β3-adrenoceptor agonists BRL 35135A and ZD2079.
Biochem.Biophys.Res.Comm. 228 605. Brawley et al (2000)
Role of endothelium/nitric oxide in atypical β-adrenoceptor-mediated relaxation in
rat isolated aorta. Eur.J.Pharmacol. 398 285. Kozlowska et
al (2003) Atypical β-adrenoceptors, different from β3-adrenoceptors, relax the rat isolated mesenteric artery.
Br.J.Pharmacol. 140 3.
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View related products by Pharmacological Action
or by Research Area
Keywords: ZD 2079, Adrenergic Receptors, B3-adrenoceptor Agonist, ZD2079, Tocris Bioscience
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