Chemical Name:(Z)-3-[(Aminoiminomethyl)thio]prop-2-enoic acid sulfate
Biological Activity:
More potent than either GABA or
muscimol as an agonist at low affinity GABAA receptors and is thus a
useful ligand to investigate GABA receptors linked to benzodiazepine receptors.
Also a GABAC receptor antagonist.
“I am grateful for your honesty and courtesy. The principles of Tocris are very different to that of your competitors who, in fact, have put our inhibitor on the market without any approval, exhibiting a pirate policy and a total absence of ethics..”
