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Category:
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7TM Receptors Peptides (Neuropeptides)Neurotensin Receptors
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Cat.No.
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Product Name
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2138 |
Xenin 8
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| Alternative name(s): |
Xenopsin-related
peptide 1 |
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XP-1 |
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Price and Availability
Click here for full price details of
Xenin 8
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Biological Activity:
C-Terminal
fragment of xenin, a neurotensin-like peptide; modulates pancreatic insulin and
glucagon secretion/effects. Stimulates basal and arginine-induced insulin
secretion and potentiates the insulin response to glucose (EC50 =
0.16 nM). Also potentiates arginine- and carbachol-induced glucagon secretion
in a somatostatin-independent manner.
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
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References:
Carraway et al (1988) Xenopsin-related peptide generated in avian
gastric extracts. Regul.Pept. 22 303. Feurle et al
(2003) Metabolism and potency of xenin and of its reduced hexapseudopeptide y
fragment in dog. Life Sci. 74 697. Silvestre et al (2003)
Stimulatory effect of xenin-8 on insulin and glucagon secretion in the perfused
rat pancreas. Regul.Pept. 115 25.
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or by Research Area
Keywords: Xenin 8, Peptides (Neuropeptides), Neurotensin-like Peptide; Potentiates Insulin & Glucagon Secretion, Xenopsin-related Peptide 1, XP-1, Tocris Bioscience
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