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Category:
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7TM Receptors Adrenergic ReceptorsBeta-1 Receptors
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Cat.No.
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Product Name
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0950 |
Xamoterol hemifumarate
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ICI
118,587 |
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Price and Availability
Click here for full price details of
Xamoterol hemifumarate
Other Information:
Sold with the permission of AstraZeneca UK Ltd
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Chemical Name:
1-(4-Hydroxyphenoxy)-3-[2-(4-morpholinocarboxamido)ethy
lamino]-2-propanol hemifumarate |
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Biological Activity:
β1-adrenoceptor-selective
partial agonist (pA2 values are 7.4-7.8 and 5.2-6.2 at β1-
and β2-adrenoceptors
respectively).
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
Certificate of Analysis is currently unavailable on-line. Please contact Customer Service
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References:
Barlow et al (1981) β-Adrenoceptor stimulant properties of
aminoalkylamino-substituted 1-aryl-2-ethanols and 1-(aryloxy)-2-propanols.
J.Med.Chem. 24 315. Nuttall and Snow (1982) The
cardiovascular effects of ICI 118,587: a β1-adrenoceptor partial
agonist. Br.J.Pharmacol. 77 381. Malta et al (1985)
The in vitro pharmacology of xamoterol (ICI 118,587). Br.J.Pharmacol. 85
179.
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View related products by Pharmacological Action
or by Research Area
Keywords: Xamoterol Hemifumarate, Adrenergic Receptors, B1 Selective Partial Agonist , ICI 118,587, Tocris Bioscience
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