|
Category:
|
Enzymes Proteases MMP
|
|
Cat.No.
|
Product Name
|
|
2633 |
WAY 170523
|
|
|
|
Price and Availability
Click here for full price details of
WAY 170523
|
|
Chemical Name:
N-[2-[4-[[[2-[(Hydroxyamino)carbonyl]-4,6-dimethylpheny
l](phenylmethyl)amino]sulfonyl]phenoxy]ethyl]-2-benzofu
rancarboxamide |
|
|
Biological Activity:
Potent and selective inhibitor of
MMP-13 (IC50 values are 17, 945, > 1000 and > 10000 nM for
MMP-13, MMP-9, TACE and MMP-1 respectively).
|
Technical Data:
|
|
|
Resources:
|
|
Certificate of Analysis / MSDS:
|
References:
Chen et
al (2000) Structure-based design of a novel, potent, and selective
inhibitor for MMP-13 utilizing NMR spectroscopy and computer-aided molecular
design. J.Am.Chem.Soc. 122 9648.
|
|
View related products by Pharmacological Action
or by Research Area
Keywords: WAY 170523, Proteases, Potent & Selective Inhibitor Of MMP-13, WAY170523, Tocris Bioscience
|
|
Literature in this Area Signal Transduction Guide | A complete listing of signal transduction products available from Tocris, including descriptions on selected tools and unit sizes. | | View PDF |
Product Feature
MMP Inhibitors
Key MMP Inhibitors available from Tocris include:
|