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Category: EnzymesarrowProteasesarrowMMP
Cat.No. Product Name
2633 WAY 170523
Price and Availability

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WAY 170523
Chemical Name: N-[2-[4-[[[2-[(Hydroxyamino)carbonyl]-4,6-dimethylpheny l](phenylmethyl)amino]sulfonyl]phenoxy]ethyl]-2-benzofu rancarboxamide

Biological Activity:

Potent and selective inhibitor of MMP-13 (IC50 values are 17, 945, > 1000 and > 10000 nM for MMP-13, MMP-9, TACE and MMP-1 respectively).

Technical Data:

Click here for more information on batch specific data
M.Wt: 613.68
Formula: C33H31N3O7S
Storage: Desiccate at RT
Solubility: Soluble to 100 mM in DMSO and to 100 mM in Ethanol
Purity: >99%
CAS No: [307002-73-9]

Resources:

  • Certificate of Analysis / MSDS:

    Certificate of Analysis: View current batch
    Product/Material Safety Data Sheet: View current batch

    References:

    Chen et al (2000) Structure-based design of a novel, potent, and selective inhibitor for MMP-13 utilizing NMR spectroscopy and computer-aided molecular design. J.Am.Chem.Soc. 122 9648.
    View related products by Pharmacological Action or by Research Area

    Keywords: WAY 170523, Proteases, Potent & Selective Inhibitor Of MMP-13, WAY170523, Tocris Bioscience

    Literature in this Area
    Signal Transduction Guide
    Signal Transduction Guide : An informative guide for all scientists working in: Cell cycle & apoptosis, Protein kinases & phosphatases, Ion channels, Calcium & lipid signaling, Cyclic nucleotides & G-proteins, Nitric oxide, & Signaling EnzymesA complete listing of signal transduction products available from Tocris, including descriptions on selected tools and unit sizes.
    View PDF
    Product Feature
    MMP Inhibitors
    Key MMP Inhibitors available from Tocris include:
    2631   Marimastat
    Broad spectrum MMP inhibitor
    2621   ARP 100
    Selective inhibitor of MMP-2
    2633   WAY 170523
    Selective inhibitor of MMP-13
    View Product Feature
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