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Category: Cellular Processes and ComponentsarrowCytoskeleton and Motor ProteinsarrowMicrotubules
Cat.No. Product Name
1256 Vinblastine sulfate
Price and Availability

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Vinblastine sulfate
Chemical Name: Vincaleukoblastine

Biological Activity:

Anticancer agent; microtubule disrupter. Induces apoptosis in cultured hepatocytes and human lymphoma cells.

Technical Data:

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M.Wt: 909.06
Formula: C46H58N4O9.H2SO4
Storage: Desiccate at +4°C
Solubility: Soluble to 100 mM in Water
CAS No: [143-67-9]

Resources:

  • Certificate of Analysis / MSDS:

    Certificate of Analysis: View current batch
    Product/Material Safety Data Sheet: View current batch

    References:

    Jordan et al (1985) Comparison of the effects of vinblastine, vincristine, vindesine, and vinepidine on microtubule dynamics and cell proliferation in vitro. Cancer Res. 45 2741. Tsukidate et al (1993) Microtubule antagonists activate programmed cell death (apoptosis) in cultured rat hepatocytes. Am.J.Pathol. 143 918. Rai and Wolf (1998) Localization of critical histidyl residues required for vinblastine-induced tubulin polymerization and for microtubulin assembly. J.Biol.Chem. 273 31131.
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    Keywords: Vinblastine Sulfate, Cytoskeleton & Motor Proteins, Disrupts Microtubules, Tocris Bioscience

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