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Category: Ion ChannelsarrowCalcium ChannelsarrowVoltage-gated Calcium Channels
Cat.No. Product Name
0654 Verapamil hydrochloride  
Price and Availability

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Verapamil hydrochloride
Chemical Name: a-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl] -3,4-dimethoxy-a-(1-methylethyl)benzeneacetonitrile hydrochloride

Biological Activity:

L-type calcium channel blocker. Vasodilator, adrenergic antagonist.

Technical Data:

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M.Wt: 491.07
Formula: C27H38N2O4.HCl
Storage: Store at RT
Solubility: Soluble to 50 mM in Ethanol and to 100 mM in Water
Purity: >99%
CAS No: [152-11-4]

Resources:

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    References:

    Merck Index 12 10083. Ishibashi et al (1995) Block of P-type Ca2+ channels in freshly dissociated rat cerebellar Purkinje neurons by diltiazem and verapamil. Brain Res. 695 88. Lacinova et al (1995) Interaction of RO-40-5967 and verapamil with the stably expressed alpha 1 subunit of the cardiac L-type calcium channel. J.Pharmacol.Exp.Ther. 274 54. Ustunes et al (1996) Effects of verapamil on intimal thickening and vascular reactivity in the collared carotid artery of the rabbit. Br.J.Pharmaocl. 118 1681.
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    Keywords: Verapamil Hydrochloride, Calcium Channels, Ca2+ Channel Blocker (L-type), Tocris Bioscience

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