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Category: Ion ChannelsarrowPotassium ChannelsarrowCa2+-Activated Potassium Channels
Cat.No. Product Name
2661 UCL 2077
Price and Availability

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UCL 2077
Chemical Name: N-Trityl-3-pyridinemethanamine

Biological Activity:

Slow afterhyperpolarisation (sAHP) channel blocker; reduces sAHP in hippocampal slice preparations. Displays no effect on Ca2+ currents or the time course of sAHP/sIAHP.

Technical Data:

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M.Wt: 350.46
Formula: C25H22N2
Storage: Store at RT
Solubility: Soluble to 50 mM in DMSO and to 25 mM in Ethanol
Purity: >99%

Resources:

  • Certificate of Analysis / MSDS:

    Certificate of Analysis: View current batch
    Product/Material Safety Data Sheet: View current batch

    References:

    Shah et al (2006) Enhancement of hippocampal pyramidal cell excitability by the novel selective slow-afterhyperpolarization channel blocker 3-(triphenylmethylaminomethyl)pyridine (UCL2077). Mol.Pharmacol. 70 1494.
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    Keywords: UCL 2077, Potassium Channels, Slow Afterhyperpolarisation (sAHP) Channel Blocker, UCL2077, Tocris Bioscience

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