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Category: Ion ChannelsarrowLigand-gated Ion ChannelsarrowGlutamate (Ionotropic) ReceptorsarrowNMDA SelectivearrowNMDA SitearrowAgonists
Cat.No. Product Name
0312 (RS)-(Tetrazol-5-yl)glycine  
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(RS)-(Tetrazol-5-yl)glycine

Biological Activity:

Potent NMDA receptor agonist, approximately 20 times more active than NMDA.

Technical Data:

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M.Wt: 143.1
Formula: C3H5N5O2
Storage: Store at RT
Solubility: Soluble to 50 mM in Water
CAS No: [138199-51-6]

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    References:

    Schoepp et al (1991) D,L-(Tetrazol-5-yl)glycine a novel and highly potent NMDA receptor agonist. Eur.J.Pharmacol. 203 237. Arnt et al (1995) Diffentiation of in vivo effects of AMPA and NMDA receptor ligands using drug discrimination methods and convulsant/anticonvulsant activity. Eur.J.Pharmacol. 285 289. Moroni et al (1995) NMDA receptor heterogeneity in mammalian tissues: focus on two agonists, (2S,3R,4S)cyclopropylglutamate and the sulfate ester of 4-hydroxy-(S)-pipecolic acid. Naunyn-Schmied.Arch.Pharmacol. 351 371.
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    Keywords: (RS)-(Tetrazol-5-yl)glycine, Ligand-gated Ion Channels, Highly Potent NMDA Receptor Agonist, (Tetrazol-5-yl)glycine, Tocris Bioscience
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