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Category: Cellular Processes and ComponentsarrowApoptosisarrowApoptosis Inducer
Cat.No. Product Name
1621 Streptozocin
Alternative name(s): Streptozotocin
Price and Availability

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Streptozocin
Chemical Name: 2-Deoxy-2-[[(methylnitrosoamino)carbonyl]amino]-D-gluco se

Biological Activity:

Antibiotic and antitumor agent. Alkylates DNA and induces diabetes mellitus via reduction of nicotinamide adenine dinucleotide in pancreatic β-cells in vivo.

Technical Data:

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M.Wt: 265.22
Formula: C8H15N3O7
Storage: Desiccate at -20°C
Solubility: Soluble to 100 mM in Water
CAS No: [18883-66-4]

Resources:

  • Certificate of Analysis / MSDS:

    Certificate of Analysis: View current batch
    Product/Material Safety Data Sheet: View current batch

    References:

    Bennett and Pegg (1981) Alkylation of DNA in rat tissues following administration of streptozotocin. Cancer Res. 41 2786. Weis (1982) Steptozotocin: A review of its pharmacology, efficacy and toxicity. Cancer Treat. Rep. 66 427.
    View related products by Pharmacological Action or by Research Area

    Keywords: Streptozocin, Apoptosis, DNA Alkylator; Antitumour & Induces Diabetes, Streptozotocin, Tocris Bioscience

    Literature in this Area
    Signal Transduction Guide
    Signal Transduction Guide : An informative guide for all scientists working in: Cell cycle & apoptosis, Protein kinases & phosphatases, Ion channels, Calcium & lipid signaling, Cyclic nucleotides & G-proteins, Nitric oxide, & Signaling EnzymesA complete listing of signal transduction products available from Tocris, including descriptions on selected tools and unit sizes.
    View PDF
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