Sotalol Hydrochloride | Adrenergic Receptors | B Antagonist

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Cat.No.	Product Name
0952	Sotalol hydrochloride

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Sotalol hydrochloride

Chemical Name: N-[4-[1-Hydroxy-2-[(1-methylethyl)amino]ethyl]phenyl]me thanesulfonamide hydrochloride

Biological Activity:

A relatively potent pure β adrenergic antagonist, unique in possessing additional class III antiarrhythmic activity.

Technical Data:

M.Wt:	308.82
Formula:	C₁₂H₂₀N₂O₃S.HCl
Storage:	Store at RT
Solubility:	Soluble to 50 mM in Water
Purity:	>99%
CAS No:	[959-24-0]

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References:

Merck Index 12 8876. Uloth et al (1966) Sulfonanilides. I. Monoalkyl- and arylsulfonamidophenethanolamines. J.Med.Chem. 9 88. Claudel and Touboul (1995) Sotalol: from 'just another beta blocker' to 'the prototype class III antidysrhythmic compound'. Pacing Clin.Electrophysiol. 18 451. Fiset et al (1997) Block of I_ks by the diuretic agent indapamide modulates cardiac electrophysiological effects of the class III antiarrhythmic drug dl-sotalol. J.Pharmacol.Exp.Ther. 283 148.

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Keywords: Sotalol Hydrochloride, Adrenergic Receptors, B Antagonist , Tocris Bioscience

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Scientific Reviews

Adrenoceptor Pharmacology
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