Sertraline | Neurotransmitter Transporters | 5-HT Re-uptake Inhibitor

Category:

Cat.No.	Product Name
2395	Sertraline hydrochloride

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Sertraline

Chemical Name: (1S,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-met hyl-1-naphthalenamine hydrochloride

Biological Activity:

Potent, orally active selective serotonin re-uptake inhibitor (SSRI) used clinically to treat depression.

Technical Data:

M.Wt:	342.69
Formula:	C₁₇H₁₇Cl₂N.HCl
Storage:	Desiccate at RT
Solubility:	Soluble to 5 mM in Water and to 100 mM in DMSO
Purity:	>99%
CAS No:	[79559-97-0]

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Certificate of Analysis / MSDS:

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References:

Koe et al (1983) Sertraline, 1S,4S-N-methyl-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthylamine, a new uptake inhibitor with selectivity for serotonin. J.Pharmacol.Exp.Ther. 226 686. Heym and Koe (1988) Pharmacology of sertraline: a review. J.Clin.Psychiatry 49 40. Doogan and Caillard (1988) Sertraline: a new antidepressant. J.Clin.Psychiatry. 49 46.

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Keywords: Sertraline, Neurotransmitter Transporters, 5-HT Re-uptake Inhibitor, Tocris Bioscience

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