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Category:
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Enzymes CyclaseAdenylyl Cyclase
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Cat.No.
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Product Name
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1435 |
SQ 22536
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Price and Availability
Click here for full price details of
SQ 22536
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Chemical Name:
9-(Tetrahydro-2-furanyl)-9H-purin-6-amine |
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Biological Activity:
Inhibitor
of adenylyl cyclase (IC50 = 1.4 μM). Inhibits PGE1-stimulated
increases in cAMP levels in intact human platelets.
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
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References:
Harris et al (1979) Inhibition of
adenylate cyclase in human blood platelets by 9-substituted adenine
derivatives. J.Cyclic Nucleotide Res. 5 125. Fabbri et
al (1991) Inhibition of adenylate cyclase of catfish and rat hepatocyte
membranes by 9-(tetrahydro-2-furyl)adenine (SQ 22536). J.Enz.Inhib. 5
87. Hourani et al (2001) Role of cyclic nucleotides in
vasodilations of the rat thoracic aorta induced by adenosine analogues.
Br.J.Pharmacol. 133 833.
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Keywords: SQ 22536, Cyclase, Adenylyl Cyclase Inhibitor, SQ22536, Tocris Bioscience
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Literature in this Area Signal Transduction Guide | A complete listing of signal transduction products available from Tocris, including descriptions on selected tools and unit sizes. | | View PDF |
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