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Category: Ion ChannelsarrowLigand-gated Ion ChannelsarrowGABAA and GABAC ReceptorsarrowGABAA ReceptorsarrowOther
Cat.No. Product Name
2143 SCS
Price and Availability

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SCS
Chemical Name: Salicylidene salicylhydrazide

Biological Activity:

Potent and selective partial inhibitor of β1-containing GABAA receptors (IC50 values are 4.5, 5.3 and 7.9 nM at α2β1γ1q, a2β1γ1 and α2β1γ2s GABAA receptors respectively). May bind allosterically to a novel site on GABAA receptor.

Technical Data:

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M.Wt: 256.26
Formula: C14H12N2O3
Storage: Store at RT
Solubility: Soluble to 50 mM in DMSO
CAS No: [3232-36-8]

Resources:

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    • Certificate of Analysis / MSDS:

    Certificate of Analysis: View current batch
    Product/Material Safety Data Sheet: View current batch

    References:

    Thompson et al (2004) Salicylidene salicylhydrazide, a selective inhibitor of β1-containing GABAA receptors. Br.J.Pharmacol. 142 97.
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    Keywords: SCS, Ligand-gated Ion Channels, Selective Inhibitor Of GABAA Receptor; B1-subunit-selective, Tocris Bioscience
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