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Category:
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Transporters Neurotransmitter TransportersAdrenergic Transporters
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Cat.No.
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Product Name
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2742 |
Reserpine
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Price and Availability
Click here for full price details of
Reserpine
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Chemical Name:
(3b,16b,17a,18b,20a)-11,17-Dimethoxy-18-[(3,4,5-trimeth
oxybenzoyl)oxy]yohimban-16-carboxylic acid methyl ester |
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Biological Activity:
Binds the vesicular monoamine
transporter (VMAT2) and inhibits transport of biogenic amines into adrenal
chromaffin granules and synaptic vesicles. Causes depletion of biogenic amine
stores. Antihypertensive and antipsychotic.
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
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References:
Schuldiner et al (1993) Reserpine binding to a vesicular amine transporter
expressed in chinese hamster ovary fibroblasts. J.Biol.Chem. 268
29. Heslop and Curzon (1999) Effect of reserpine on behavioural
responses to agonists at 5-HT1A, 5-HT1B, 5-HT2A,
and 5-HT2C receptor subtypes. Neuropharmacology 38
883. Metzger et al (2002) Inhibitory effect of reserpine on
dopamine transporter function. Eur.J.Pharmacol. 456 39.
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View related products by Pharmacological Action
or by Research Area
Keywords: Reserpine, Neurotransmitter Transporters, Inhibitor Of Vesicular Monoamine Transport, Tocris Bioscience
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Product Feature
Uptake Inhibitors
Key Uptake Inhibitors now available from Tocris include:
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