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Category: 7TM Receptorsarrow5-HT Receptorsarrow5-HT1 Receptorsarrow5-HT1B
Cat.No. Product Name
0912 RU 24969 hemisuccinate  
Price and Availability

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RU 24969 hemisuccinate
Chemical Name: 5-Methoxy-3-(1,2,5,6-tetrahydro-4-pyridinyl)-1H-indole hemisuccinate

Biological Activity:

Potent 5-HT1A/1B and moderate 5-HT2C agonist that may also release 5-HT. Centrally active following systemic administration.

Technical Data:

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M.Wt: 287.34
Formula: C14H16N2O.½C4H6O4
Storage: Store at RT
Solubility: Soluble to 50 mM in DMSO and to 50 mM in Water
Purity: >99%
CAS No: [107008-28-6]

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    References:

    Guillaume et al (1987) Synthesis of 3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indoles and study of their serotonergic and antidopaminergic properties. Eur.J.Med.Chem. 22 33. Gudermann et al (1993) Human S31 serotonin receptor clone encodes a 5-hydroxytryptamine1E-like serotonin receptor. Mol.Pharmacol. 43 412. Tomkins and O'Neill (2000) Effect of 5-HT(1B) receptor ligands on self-administration of ethanol in an operant procedure in rats. Pharmacol.Biochem.Behav. 66 129.
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    Keywords: RU 24969 Hemisuccinate, 5-HT Receptors, 5-HT1B / 1A Agonist, RU24969 Hemisuccinate, Tocris Bioscience
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