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Category:
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Ion Channels Sodium ChannelsVoltage-gated Sodium Channels
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Cat.No.
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Product Name
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2313 |
QX 314 chloride
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Price and Availability
Click here for full price details of
QX 314 chloride
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Chemical Name:
N-(2,6-Dimethylphenylcarbamoylmethyl)triethylammonium
chloride |
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Biological Activity:
Membrane impermeable quaternary
derivative of lidocaine, a blocker of voltage-activated Na+
channels.
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
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References:
Stichartz et al (1973) The inhibition of sodium
currents in myelinated nerve by quaternary derivatives of lidocaine.
J.Gen.Physiol. Alreja and Aghajanian (1994) QX-314 blocks the potassium
but not the sodium dependent components of the opiate response in locus
coeruleus neurons. Brain Res. 639 320. Perkins and Wong
(1995) Intracellular QX-314 blocks the hyperpolarization activated inward
current Iq in hippocampal CA1 pyramidal cells. J.Neurophysiol. 72
911.
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View related products by Pharmacological Action
or by Research Area
Keywords: QX 314 Chloride, Sodium Channels, Na+ Channel Blocker, QX314 Chloride, Tocris Bioscience
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Literature in this Area Signal Transduction Guide | A complete listing of signal transduction products available from Tocris, including descriptions on selected tools and unit sizes. | | View PDF |
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