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Category: Nuclear ReceptorsarrowPPAR Receptors
Cat.No. Product Name
2306 15-deoxy-D-12,14-Prostaglandin J2
Price and Availability

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15-deoxy-D-12,14-Prostaglandin J2
Chemical Name: (5Z,12E,14E)-11-Oxo-prosta-5,9,12,14-tetraen-1-oic acid

Biological Activity:

Selective PPARγ agonist that induces adipocyte differentiation in C3H10Y1/2 fibroblasts (EC50 = 7 μM).

Technical Data:

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M.Wt: 316.44
Formula: C20H28O3
Storage: Store at -20°C
Solubility: Soluble to 25 mM in DMSO and to 25 mM in Ethanol
CAS No: [87893-55-8]

Resources:

  • Certificate of Analysis / MSDS:

    Certificate of Analysis is currently unavailable on-line. Please contact Customer Service
    Product/Material Safety Data Sheet: View current batch

    References:

    Forman et al (1995) 15-Deoxy-D12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPARγ. Cell 83 803. Kliewer et al (1995) A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor γ and promotes adipocyte differentiation. Cell 83 813.
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    Keywords: 15-deoxy-D-12,14-Prostaglandin J2, PPAR Receptors, Endogenous PPARg Agonist, 15deoxy-D-12,14-Prostaglandin J2, Tocris Bioscience

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