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Category:
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Enzymes ReductasesHMG-CoA Reductase
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Cat.No.
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Product Name
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2318 |
Pravastatin sodium salt
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| Alternative name(s): |
Eptastatin sodium |
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Price and Availability
Click here for full price details of
Pravastatin
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Chemical Name:
(bR,dR,1S,2S,6S,8S,8aR)-1,2,6,7,8,8a-Hexahydro-b,d,6-tr
ihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-napht
haleneheptanoic acid monosodium salt |
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Biological Activity:
Water-soluble, competitive inhibitor of 3-hydroxy-3-methyl
coenzyme A (HMG-CoA) reductase. Potently blocks cholesterol synthesis in vivo
(Ki ~ 1 nM) and displays cardioprotective properties.
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
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References:
Hamelin and Turgeon (1998) Hydrophilicity/lipophilicity:
relevance for the pharmacology and clinical effects of HMG-CoA reductase
inhibitors. TiPS 19 26.
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View related products by Pharmacological Action
or by Research Area
Keywords: Pravastatin, Reductases, HMG-CoA Reductase Inhibitor, Eptastatin Sodium, Tocris Bioscience
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Literature in this Area Signal Transduction Guide | A complete listing of signal transduction products available from Tocris, including descriptions on selected tools and unit sizes. | | View PDF |
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