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Category: 7TM ReceptorsarrowAdrenergic ReceptorsarrowBeta-3 Receptors
Cat.No. Product Name
0994 Pindolol
Price and Availability

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Pindolol
Chemical Name: 1-(1H-Indol-4-yloxy)-3-[(1-methylethyl)amino]-2-propano l

Biological Activity:

5-HT1A/1B  receptor antagonist, with roughly equal affinity for each subtype. A partial agonist at mouse and human β3-adrenoceptors.

Technical Data:

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M.Wt: 248.32
Formula: C14H20N2O2
Storage: Store at RT
Solubility: Soluble to 100 mM in DMSO
CAS No: [13523-86-9]

Resources:

  • Certificate of Analysis / MSDS:

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    References:

    Merck Index 12 7597. Hoyer et al (1994) VII. International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (serotonin) Pharmacol.Rev. 46 157. Blin et al (1994) Structural and conformational features determining selective signal transduction in the β3-adrenergic receptor. Mol.Pharmacol. 44 1094. Corradetti et al (1998) Antagonist properties of (-)-pindolol and WAY 100635 at somatodendritic and postsynaptic 5-HT1A receptors in the rat brain. Br.J.Pharmacol. 123 449. Clifford et al (1998) Electrophysiological and neurochemical evidence that pindolol has agonist properties at the 5-HT1A autoreceptor in vivo. Br.J.Pharmacol. 124 206.
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    Keywords: Pindolol, Adrenergic Receptors, B3 Partial Agonist. Also 5-HT1A / 1B Antagonist, Tocris Bioscience

    Literature in this Area
    Scientific Reviews
    Adrenoceptor Pharmacology
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    Our laboratory loves dealing with Tocris and consider many of the compounds you sell to be far better quality than the compounds that we have received from other companies. Once again, thank you very much..”
    Researcher, Albany Medical College, USA
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