Pimozide | Dopamine Receptors | D2-like Antagonist

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Cat.No.	Product Name
0937	Pimozide

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Pimozide

Chemical Name: 1-[1-[4,4-Bis(4-fluorophenyl)butyl]-4-piperidinyl]-1,3- dihydro-2H-benzimidazol-2-one

Biological Activity:

Dopamine D₂-receptor antagonist and antipsychotic which binds with very high affinity to the cloned rat 5-HT₇ receptor (K_i = 0.5 nM).

Technical Data:

M.Wt:	461.55
Formula:	C₂₈H₂₉F₂N₃O
Storage:	Store at RT
Solubility:	Soluble to 100 mM in DMSO
CAS No:	[2062-78-4]

Resources:

Certificate of Analysis / MSDS:

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Product/Material Safety Data Sheet: View current batch

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References:

Merck 12 7589. Roth et al (1994) Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors. J.Pharmacol.Exp.Ther. 268 1403.

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Keywords: Pimozide, Dopamine Receptors, D2-like Antagonist, Tocris Bioscience

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Scientific Reviews

Dopamine Receptors
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