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Category:
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Enzymes Deaminases
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Cat.No.
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Product Name
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2033 |
Pentostatin
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| Alternative name(s): |
Deoxycoformycin |
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Price and Availability
Click here for full price details of
Pentostatin
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Chemical Name:
(8R)-3-(2-Deoxy-b-D-erythro-pentofuranosyl)-3,4,7,8-tet
rahydroimidazo[4,5-d][1,3]diazepin-8-ol |
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Biological Activity:
Irreversible inhibitor of adenosine
deaminase (Ki = 2.5 pM). Anticancer agent.
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
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References:
Klohs and Kraker (1992)
Pentostatin: future directions. Pharmacol.Rev. 44 459. Nabhan
et al (2004) Purine nucleoside analogues and combination therapies in
B-cell chronic lymphocytic leukemia: dawn of a new era. Leukemia Res. 28
429.
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View related products by Pharmacological Action
or by Research Area
Keywords: Pentostatin, Deaminases, Adenosine Deaminase Inhibitor, Deoxycoformycin, Tocris Bioscience
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Literature in this Area Signal Transduction Guide | A complete listing of signal transduction products available from Tocris, including descriptions on selected tools and unit sizes. | | View PDF |
| “I am grateful for your honesty and courtesy. The principles of Tocris are very different to that of your competitors who, in fact, have put our inhibitor on the market without any approval, exhibiting a pirate policy and a total absence of ethics..” Researcher, University of Pisa, Italy |
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