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Category: Other ActivitiesarrowSigma and ImidazolinearrowSigma LigandsarrowGeneral Sigma
Cat.No. Product Name
0620 4-PPBP maleate  
Price and Availability

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4-PPBP maleate
Chemical Name: 4-Phenyl-1-(4-phenylbutyl)piperidine maleate

Biological Activity:

σ ligand and selective non-competitive antagonist at recombinant NR1a/2B NMDA receptors expressed in Xenopus oocytes.

Technical Data:

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M.Wt: 409.52
Formula: C21H27N.C4H4O4
Storage: Store at RT
Solubility: Soluble to 25 mM in Ethanol and to 25 mM in DMSO

Resources:

  • Certificate of Analysis / MSDS:

    Certificate of Analysis: View current batch
    Product/Material Safety Data Sheet: View current batch
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    References:

    Glennon et al (1991) Novel 1-phenylpiperazine and 4-phenylpiperidine derivatives as high affinity σ ligands. J.Med.Chem. 34 3360. Whittemore et al (1997) Antagonism of N-methyl-D-aspartate receptors by σ site ligands: potency, subtype-selectivity and mechanisms of inhibition. J.Pharmacol.Exp.Ther. 282 326.
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    Keywords: 4-PPBP Maleate, Sigma & Imidazoline, Specific S Ligand, NMDA Antagonist, 4PPBP Maleate, Tocris Bioscience

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