|
Category:
|
Enzymes ATPases/GTPasesATPase
|
|
Cat.No.
|
Product Name
|
|
2689 |
POM 1
|
|
|
|
Price and Availability
Click here for full price details of
POM 1
|
|
Chemical Name:
Sodium metatungstate |
|
|
Biological Activity:
Inhibitor of Ecto-NTPDases that displays minor
selectivity for NTPDases 1 and 2 over NTPDase 3 and P2Y12 (Ki
values are 2.58, 3.26, > 10 and 28.8 μM for NTPDase
1, NTPDase 3, P2Y12 and NTPDase 2 respectively). Abolishes renal
protection induced by ischaemic preconditioning.
|
Technical Data:
|
|
|
Resources:
|
|
Certificate of Analysis / MSDS:
Certificate of Analysis is currently unavailable on-line. Please contact Customer Service
|
|
|
References:
Muller et
al (2006) Polyoxometalates - a new class of potent ecto-nucleoside
triphosphate diphosphohydrolase (NTPDase) inhibitors. Bioorg.Med.Chem.Lett. 16
5943. Grenz et al (2007) Contribution of E-NTPDase1 (CD39) to
renal protection from ischemia-reperfusion injury. FASEB J. 21
2863.
|
|
View related products by Pharmacological Action
or by Research Area
Keywords: POM 1, ATPases / GTPases, Inhibitor Of E-NTPDases, POM1, Tocris Bioscience
|
|
Literature in this Area Signal Transduction Guide | A complete listing of signal transduction products available from Tocris, including descriptions on selected tools and unit sizes. | | View PDF |
Connecting Targets to Molecules
Target Detective is an innovative searchable resource that connects biological targets to research tools.
Search by receptor, enzyme, protein and gene data terms to identify Target Files or Target Families.
Pinpoint the most relevant research tools for your target in seconds!
Visit Target Detective Now!
|
