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Category:
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Enzymes EsterasesPhospholipase
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Cat.No.
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Product Name
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1460 |
PACOCF3
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| Alternative name(s): |
Palmityl trifluoromethyl ketone |
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Price and Availability
Click here for full price details of
PACOCF3
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Chemical Name:
1,1,1-Trifluoro-2-heptadecanone |
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Biological Activity:
Phospholipase A2 inhibitor. Can also
alter Ca2+ signalling in renal tubular cells.
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
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References:
Ackermann et al
(1995) Inhibition of macrophage Ca2+-independent phospholipase A2
by bromoenol lactone and trifluoromethyl ketones. J.Biol.Chem. 270
445. Lio et al (1996) Irreversible inhibition of
Ca(2+)-independent phospholipase A2 by methyl arachidonyl
fluorophosphonate. Biochim.Biophys.Acta 1302 55. Jan et
al (2000) Dual action of palmitoyl trifluoromethyl ketone (PACOCF3)
on Ca2+ signaling: activation of extracellular Ca2+
influx and alteration of ATP- and bradykinin-induced Ca2+ responses
in Madin Darby canine kidney cells. Arch.Toxicol. 74 447.
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Keywords: PACOCF3, Esterases, Phospholipase A2 Inhibitor, Palmityl Trifluoromethyl Ketone, Tocris Bioscience
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Literature in this Area Signal Transduction Guide | A complete listing of signal transduction products available from Tocris, including descriptions on selected tools and unit sizes. | | View PDF |
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