Oxyntomodulin | Peptides (Gastrointestinal) | Endogenous Gut Peptide; Modulates Feeding & Metabolism | Glucagon (1-37) | Enteroglucagon

Category:

7TM Receptors

Peptides (Gastrointestinal)

Glucagon and Related Peptide Receptors

Other Glucagon

Cat.No.

Product Name

2094

Oxyntomodulin

Alternative name(s):	Glucagon (1-37)
	Enteroglucagon

Price and Availability

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Oxyntomodulin

Biological Activity:

Endogenous glucagon-like peptide that modulates feeding and metabolism; secreted by intestinal L-cells. Increases cAMP production and inhibits gastric acid secretion in rat stomach. Also inhibits intestinal glucose absorption. Reduces fasting ghrelin levels following peripheral administration and reduces food intake and weight gain in rats following central or peripheral administration in vivo.

Technical Data:

M.Wt:	4421.86
Formula:	C₁₉₂H₂₉₅N₅₉O₆₀S
Storage:	Desiccate at -20°C
CAS No:	[62340-29-8]

Resources:

Certificate of Analysis / MSDS:

Certificate of Analysis: View current batch

Product/Material Safety Data Sheet: View current batch

References:

Bataille et al (1981) Bioactive enteroglucagon (oxyntomodulin): present knowledge on its chemical structure and its biological activities. Peptides 2 41. Stumpel et al (1997) A new role for enteric glucagon-37: acute stimulation of glucose absorption in rat small intestine. FEBS Lett. 410 515. Dakin et al (2004) Peripheral oxyntomodulin reduces food intake and body weight gain in rats. Endocrinology 145 2687. Stanley et al (2004) Gastrointestinal satiety signals. III. Glucagon-like peptide 1, oxyntomodulin, peptide YY, and pancreatic polypeptide. Am.J.Physiol.Gastrointest.Liver Physiol. 286 G693.

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Keywords: Oxyntomodulin, Peptides (Gastrointestinal), Endogenous Gut Peptide; Modulates Feeding & Metabolism, Glucagon (1-37), Enteroglucagon, Tocris Bioscience

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