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Category:
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7TM Receptors Cannabinoid ReceptorsCB1 Receptors
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Cat.No.
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Product Name
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1655 |
O-2050
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Price and Availability
Click here for full price details of
O-2050
Other Information:
Sold under licence from VCU-IPF
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Chemical Name:
(6aR,10aR)-3-(1-Methanesulfonylamino-4-hexyn-6-yl)-6a,7
,10,10a-tetrahydro-6,6,9-trimethyl-6H-dibenzo[b,d]pyran |
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Biological Activity:
High
affinity cannabinoid CB1 receptor silent antagonist (Ki =
2.5 nM); devoid of agonist effects. Produces suppression of spontaneous
activity but does not produce nociception or hypothermia in vivo.
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
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References:
Martin et al (2002) Agonists and
silent antagonists in a series of cannabinoid sulfonamides. Symposium
on the Cannabinoids, International Cannabinoid Research Society.
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View related products by Pharmacological Action
or by Research Area
Keywords: O-2050, Cannabinoid Receptors, CB1 Silent Antagonist, O2050, Tocris Bioscience
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