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Category: EnzymesarrowSynthases/SynthetasesarrowNO SynthasesarrowNon-Selective NOS
Cat.No. Product Name
0602 7-Nitroindazole  
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7-Nitroindazole

Biological Activity:

Reversible, competitive and non-selective NOS inhibitor.

Technical Data:

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M.Wt: 163.14
Formula: C7H5N3O2
Storage: Desiccate at -20°C
Solubility: Soluble to 100 mM in DMSO and to 20 mM in Ethanol
Purity: >99%
CAS No: [2942-42-9]

Resources:

  • Certificate of Analysis / MSDS:

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    References:

    Moore et al (1993) 7-nitroindazole, an inhibitor of nitric oxide synthase, exhibits antinociceptive activity in the mouse without increasing blood pressure. Br.J.Pharmacol. 108 296. Moore et al (1993) Characterisation of the novel nitric oxide synthase inhibitor 7-nitroindazole and related indazoles: antinociceptive and cardiovascular effects. Br.J.Pharmacol. 110 219. Babbedge et al (1993) Inhibition of rat cerebellar nitric oxide synthase by 7-nitroindazole and related substituted indazoles. Br.J.Pharmacol. 110 225. Moore and Handy (1997) Selective inhibitors of neuronal nitric oxide synthase - is no NOS really good NOS for the nervous system? TiPS 18 204.

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    Keywords: 7-Nitroindazole, Synthases / Synthetases, Non-selective NOS Inhibitor, 7Nitroindazole, Tocris Bioscience

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    Signal Transduction Guide : An informative guide for all scientists working in: Cell cycle & apoptosis, Protein kinases & phosphatases, Ion channels, Calcium & lipid signaling, Cyclic nucleotides & G-proteins, Nitric oxide, & Signaling EnzymesA complete listing of signal transduction products available from Tocris, including descriptions on selected tools and unit sizes.
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    Our laboratory loves dealing with Tocris and consider many of the compounds you sell to be far better quality than the compounds that we have received from other companies. Once again, thank you very much..”
    Researcher, Albany Medical College, USA
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