[bAla⁸]-Neurokinin A(4-10)

Alternative name(s):

MEN 10210

[bAla8]- Neurokinin A(4-10) C35H56N8O10S

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[bAla8]- Neurokinin A(4-10)

Biological Activity:

NK₂ receptor agonist (pD₂ = 6.91). Produces bladder contraction and bronchospasm in guinea pigs in vivo.

Technical Data:

M.Wt:	780.93
Formula:	C₃₅H₅₆N₈O₁₀S
Storage:	Desiccate at -20°C
CAS No:	[122063-01-8]

Resources:

Certificate of Analysis / MSDS:

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References:

Rovero et al (1989) A potent and selective agonist for NK-2 tachykinin receptor. Peptides 10 593. Maggi et al (1990) In vivo pharmacology of [βAla⁸]neurokinin A-(4-10), a selective NK-2 tachykinin receptor agonist. Eur.J.Pharmacol. 177 81. Carini et al (2001) Tachykinin NK₂ receptors and enhancement of cholinergic transmission in the inflamed rat colon: an in vivo motility study. Br.J.Pharmacol. 133 1107.

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Keywords: [bAla8]- Neurokinin A(4-10), Peptides (Neuropeptides), NK2 Agonist, MEN 10210, Tocris Bioscience

Literature in this Area

Scientific Reviews

Tachykinin Receptor Compounds
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[bAla8]-Neurokinin A(4-10)