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Category:
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Cellular Processes and Components ApoptosisOther Apoptosis
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Cat.No.
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Product Name
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2324 |
Necrostatin-1
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Price and Availability
Click here for full price details of
Necrostatin-1
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Chemical Name:
5-(1H-Indol-3-ylmethyl)-3-methyl-2-thioxo-4-imidazolidi
none |
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Biological Activity:
Blocks
non-apoptotic cell death via inhibition of a specific cellular pathway,
necroptosis, which leads to necrosis (EC50 = 494 nM). Reduces
ischaemic brain injury in a mouse model of stroke.
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
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References:
Degterev
et al (2005) Chemical inhibitor of
nonapoptotic cell death with therapeutic potential for ischemic brain injury.
Nat.Chem.Biol. 1 112.
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View related products by Pharmacological Action
or by Research Area
Keywords: Necrostatin-1, Apoptosis, Novel Inhibitor Of Non-apoptotic Cell Death (necroptosis), Tocris Bioscience
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Literature in this Area Signal Transduction Guide | A complete listing of signal transduction products available from Tocris, including descriptions on selected tools and unit sizes. | | View PDF |
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