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Category:
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Enzymes ProteasesOther Proteases
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Cat.No.
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Product Name
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2647 |
NSC 632839 hydrochloride
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Price and Availability
Click here for full price details of
NSC 632839
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Chemical Name:
3,5-Bis[(4-methylphenyl)methylene]-4-piperidone
hydrochloride |
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Biological Activity:
Inhibitor of ubiquitin isopeptidase
activity that displays no effect on the proteolytic activity of the proteasome.
Induces apoptosis via a Bcl-2-dependent and apoptosome-independent pathway of
caspase activation (IC50 values are 15.65 and 16.23 μM
in E1A and E1A/C9CN cells respectively).
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
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References:
Aleo et
al (2006) Identification of new compounds that trigger
apoptosome-independent caspase activation and apoptosis. Cancer Res. 66
9235.
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View related products by Pharmacological Action
or by Research Area
Keywords: NSC 632839, Proteases, Inhibitor Of Ubiquitin Isopeptidase Activity, F6, NSC632839, Tocris Bioscience
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Literature in this Area Signal Transduction Guide | A complete listing of signal transduction products available from Tocris, including descriptions on selected tools and unit sizes. | | View PDF |
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