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Category:
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Enzymes DeacetylasesHistone Deacetylase
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Cat.No.
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Product Name
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2521 |
NSC 3852
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Price and Availability
Click here for full price details of
NSC 3852
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Chemical Name:
5-Nitroso-8-quinolinol |
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Biological Activity:
Histone deacetylase inhibitor. Causes cell differentiation and
antiproliferative activity in MCF-7 human breast cancer cells in vitro and
displays antitumour activity in vivo.
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
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References:
Martirosyan et al (2004)
Differentiation-inducing quinolines as experimental breast cancer agents in the
MCF-7 human breast cancer cell model. Biochem.Pharmacol. 68 1729.
Martirosyan et al (2006) Actions of a histone deacetylase
inhibitor NSC3852 (5-nitroso-8-quinolinol) link reactive oxygen species to cell
differentiation and apoptosis in MCF-7
human mammary tumor cells. J.Pharmacol.Exp.Ther. 317 546.
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Keywords: NSC 3852, Deacetylases, Histone Deacetylase Inhibitor, NSC3852, Tocris Bioscience
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Literature in this Area Signal Transduction Guide | A complete listing of signal transduction products available from Tocris, including descriptions on selected tools and unit sizes. | | View PDF |
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