Mianserin Hydrochloride | 5-HT Receptors | 5-HT2 Antagonist. Has Moderate Affinity For 5-ht6

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Cat.No.	Product Name
0997	Mianserin hydrochloride

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Mianserin hydrochloride

Chemical Name: 1,2,3,4,10,14b-Hexahydro-2-methyldibenzo[c,f]pyrazino[1 ,2-a]azepine hydrochloride

Biological Activity:

Non-selective 5-HT₂ receptor antagonist. Has moderate affinity for 5-ht₆. Antidepressant

Technical Data:

M.Wt:	300.83
Formula:	C₁₈H₂₀N₂.HCl
Storage:	Store at RT
Solubility:	Soluble to 10 mM in Water
CAS No:	[21535-47-7]

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References:

Merck Index 12 6260. Leonard (1982) On the mode of action of mianserin. Adv.Biochem.Psychopharmacol. 31 301. Hoyer et al (1994) VII. International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (serotonin). Pharmacol.Rev. 46 157. Newton and Elliott (1997) Mianserin-induced down-regulation of human 5-hydroxytryptamine_2A and 5-hydroxytryptamine_2C receptors stably expressed in the human neuroblastoma cell line SH-SY5Y. J.Neurochem. 69 1031.

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Keywords: Mianserin Hydrochloride, 5-HT Receptors, 5-HT2 Antagonist. Has Moderate Affinity For 5-ht6, Tocris Bioscience

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